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N-辛基吡咯烷酮

N-辛基吡咯烷酮用途

杀虫剂、棉花落叶剂，浓缩清洗剂，化学反应溶剂，药物合成介质，电子工业中的涂层剥离剂。

用作表面活性剂，能与阴离子或非离子表面活性剂复配使用，降低表面张力，提供产品性能。

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N-辛基吡咯烷酮名称

[ CAS 号 ]:
2687-94-7

[ 中文名 ]:
N-辛基吡咯烷酮

[ 英文名 ]:
N-Octylpyrrolidone

[中文别名 ]:

[英文别名 ]:

N-Octyl pyrrolidone
caprylyl pyrrolidone
T5NVTJ A8
1-octyl-pyrrolidone
2-Pyrrolidinone, 1-octyl-
1-n-octylazacyclopentan-2-one
1-Octyl-2-pyrrolidinone
N-Octylpyrrolidinone
EINECS 403-700-8
n-octyl-2-pyrrolidone

N-辛基吡咯烷酮物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
303.1±0.0 °C at 760 mmHg

[ 熔点 ]:
−25 °C(lit.)

[ 分子式 ]:
C₁₂H₂₃NO

[ 分子量 ]:
197.317

[ 闪点 ]:
129.0±9.9 °C

[ 精确质量 ]:
197.177963

[ PSA ]:
20.31000

[ LogP ]:
3.32

[ 外观性状 ]:
液体;Colorless to Yellow clear liquid

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.469

[ 储存条件 ]:
室温

N-辛基吡咯烷酮MSDS

N-辛基吡咯烷酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UY5896000

CHEMICAL NAME :: 2-Pyrrolidinone, 1-octyl-

CAS REGISTRY NUMBER :: 2687-94-7

BEILSTEIN REFERENCE NO. :: 1526318

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C12-H23-N-O

MOLECULAR WEIGHT :: 197.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,475,1988

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,475,1988 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2050 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,475,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1290-1125 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8960 mg/kg/28D-I

TOXIC EFFECTS :: Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1290-1125

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N-辛基吡咯烷酮安全信息

[ 符号 ]:

GHS05, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314-H411

[ 警示性声明 ]:
P273-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R34;R51/53

[ 安全声明 (欧洲) ]:
S23-S26-S36/37/39-S45-S1/2

[ 危险品运输编码 ]:
UN 3267 8/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
UY5896000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2933790090

N-辛基吡咯烷酮合成路线

N-辛基吡咯烷酮上下游产品

N-辛基吡咯烷酮上游产品

N-辛基吡咯烷酮下游产品

N-辛基吡咯烷酮海关

[ 海关编码 ]: 2933790090

[ 中文概述 ]:
2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:9.0% 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

N-辛基吡咯烷酮文献

Influence of the permeation enhancers 1-alkyl-2-pyrrolidones on permeant partitioning into the stratum corneum.

J. Pharm. Sci. 87(2) , 209-14, (1998)

In a previous study, the enhancing effects of a series of 1-alkyl-2-pyrrolidones (APs; 1-ethyl, 1-butyl, 1-hexyl, and 1-octyl-2-pyrrolidone) on the transport of steroidal permeants across hairless mou...

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