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1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐名称

[ CAS 号 ]:
3398-68-3

[ 中文名 ]:
1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐

[ 英文名 ]:
4-Methoxy Methamphetamine Hydrochloride

[英文别名 ]:

p-Methoxy-N,α-dimethylphenethylamine hydrochloride
p-Methoxymethamphetamine Hydrochloride
UNII:0U3N9S2CHG
EINECS 222-265-3

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐物理化学性质

[ 沸点 ]:
262.9ºC at 760 mmHg

[ 熔点 ]:
174 °C

[ 分子式 ]:
C₁₁H₁₈ClNO

[ 分子量 ]:
215.720

[ 闪点 ]:
106.6ºC

[ 精确质量 ]:
215.107697

[ PSA ]:
21.26000

[ LogP ]:
3.03850

[ 储存条件 ]:
?20°C

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐MSDS

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SH5671000

CHEMICAL NAME :: Phenethylamine, N,alpha-dimethyl-p-methoxy-, hydrochloride

CAS REGISTRY NUMBER :: 3398-68-3

LAST UPDATED :: 199007

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H17-N-O.Cl-H

MOLECULAR WEIGHT :: 215.75

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,150,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 63 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: PBBHAU Pharmacology, Biochemistry and Behavior. (ANKHO International Inc., P.O. Box 426, Fayetteville, NY 13066) V.1- 1973- Volume(issue)/page/year: 31,9,1988

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1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐安全信息

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311 + H331-H370

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 危害码 (欧洲) ]:
F,T

[ 风险声明 (欧洲) ]:
11-23/24/25-39/23/24/25

[ 安全声明 (欧洲) ]:
16-36/37-45

[ 危险品运输编码 ]:
UN1230 - class 3 - PG 2 - Methanol, solution

[ 海关编码 ]:
2922299090

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐合成路线

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐上下游产品

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐上游产品

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐下游产品

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐海关

[ 海关编码 ]: 2922299090

[ 中文概述 ]:
2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐文献

Determination of a newly encountered designer drug "p-methoxyethylamphetamine" and its metabolites in human urine and blood.

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A newly synthesized designer drug, para-methoxyethylamphetamine (PMEA) was unexpectedly detected in the postmortem specimens of fatality involving drug intoxication in 2005, Japan. For unequivocal ide...

Studies on distribution of para-methoxymethamphetamine (PMMA) designer drug in rats using gas chromatography-mass spectrometry.

Leg. Med. (Tokyo.) 11 Suppl 1 , S429-30, (2009)

para-Methoxymethamphetamine (PMMA) is an abused psychedelic compound with reports of several intoxications and deaths after ingestion. However, its pharmacokinetics based on a controlled study is unkn...

New designer drug p-methoxymethamphetamine: studies on its metabolism and toxicological detection in urine using gas chromatography-mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 789(1) , 27-41, (2003)

Studies are described on the metabolism and the toxicological analysis of the new designer drug rac-p-methoxymethamphetamine (PMMA) in rat urine using gas chromatography-mass spectrometry (GC-MS). The...

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