1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐
1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐结构式
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常用名 | 1-(4-甲氧基苯基)-N-甲基丙-2-胺盐酸盐 | 英文名 | 4-Methoxy Methamphetamine Hydrochloride |
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| CAS号 | 3398-68-3 | 分子量 | 215.720 | |
| 密度 | N/A | 沸点 | 262.9ºC at 760 mmHg | |
| 分子式 | C11H18ClNO | 熔点 | 174 °C | |
| MSDS | N/A | 闪点 | 106.6ºC | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
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Determination of a newly encountered designer drug "p-methoxyethylamphetamine" and its metabolites in human urine and blood.
Forensic Sci. Int. 177(1) , 77-84, (2008) A newly synthesized designer drug, para-methoxyethylamphetamine (PMEA) was unexpectedly detected in the postmortem specimens of fatality involving drug intoxication in 2005, Japan. For unequivocal identification, the isomeric discrimination of PMEA and its po... |
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Studies on distribution of para-methoxymethamphetamine (PMMA) designer drug in rats using gas chromatography-mass spectrometry.
Leg. Med. (Tokyo.) 11 Suppl 1 , S429-30, (2009) para-Methoxymethamphetamine (PMMA) is an abused psychedelic compound with reports of several intoxications and deaths after ingestion. However, its pharmacokinetics based on a controlled study is unknown and only partial information on its biotransformation i... |
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New designer drug p-methoxymethamphetamine: studies on its metabolism and toxicological detection in urine using gas chromatography-mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 789(1) , 27-41, (2003) Studies are described on the metabolism and the toxicological analysis of the new designer drug rac-p-methoxymethamphetamine (PMMA) in rat urine using gas chromatography-mass spectrometry (GC-MS). The identified metabolites indicated that PMMA was extensively... |
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Studies on distribution and metabolism of para-methoxymethamphetamine (PMMA) in rats after subcutaneous administration.
Toxicology 259(1-2) , 61-8, (2009) p-Methoxymethamphetamine (PMMA) is an illegal psychedelic drug of abuse derived from an amphetamine structure with a risk to health and reports of several cases of intoxications and fatalities caused by its ingestion. However, its pharmacokinetics based on a ... |
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A re-examination of the mono-methoxy positional ring isomers of amphetamine, methamphetamine and phenyl-2-propanone.
Forensic Sci. Int. 119(2) , 168-94, (2001) Recently, tablets inscribed with the Mitsubishi 3-diamond logo, and sold as 3,4-methylenedioxymethamphetamine (MDMA), were found to contain p-methoxymethamphetamine (PMMA), a compound with MDMA-like effects. Shortly after this first submission, similarly insc... |
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A preliminary behavioral investigation of PMMA, the 4-methoxy analog of methamphetamine.
Pharmacol. Biochem. Behav. 31(1) , 9-13, (1988) The controlled-substance analog N-monomethyl-1-(4-methoxyphenyl)-2-aminopropane (PMMA) may be viewed as being either the 4-methoxy analog of methamphetamine or the N-methyl analog of 1-(4-methoxyphenyl)-2-aminopropane (PMA). Because of its abuse potential, PM... |
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Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.
Drug Metab. Dispos. 32(4) , 379-81, (2004) p-Methoxymethamphetamine (PMMA) is a new designer drug, listed in many countries as a controlled substance. Several fatalities have been attributed to the abuse of this designer drug. Previous in vivo studies using Wistar rats had shown that PMMA was metaboli... |
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Behavioral, hyperthermic and pharmacokinetic profile of para-methoxymethamphetamine (PMMA) in rats.
Pharmacol. Biochem. Behav. 98(1) , 130-9, (2011) Despite poisoning with the ecstasy substitute para-methoxymethamphetamine (PMMA) being typically associated with severe hyperthermia and death, behavioral and toxicological data on this drug are missing. Herein we present the behavioral profile of PMMA, its h... |
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Evaluation of the neurotoxicity of N-methyl-1-(4-methoxyphenyl)-2-aminopropane (para-methoxymethamphetamine, PMMA).
Brain Res. 589(2) , 349-52, (1992) These studies assessed the neurotoxic potential of N-methyl-1-(4-methoxyphenyl)-2-aminopropane (para-methoxymethamphetamine; PMMA), an amphetamine analog that has surfaced in the illicit drug market. Repeated subcutaneous injections of PMMA caused lasting, do... |