4,5-二氯儿茶酚

4,5-二氯儿茶酚用途

4,5-Dichlorocatechol 是一种广谱的 pseudomonas chlororaphis RW71 氯邻苯二酚 1,2-二加氧酶的底物。对降解 Chlorobenzoate 的 Pseudomonas putida AC27 菌株双加氧酶的 Ki 值为 30 nM,对 Acidovorax PS14 菌株双加氧酶的 Ki 值为 30 nM。

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4,5-二氯儿茶酚名称

[ CAS 号 ]:
3428-24-8

[ 中文名 ]:
4,5-二氯儿茶酚

[ 英文名 ]:
4,5-Dichlorocatechol

[中文别名 ]:

4,5-二氯邻苯二酚

[英文别名 ]:

Pyrocatechol,4,5-dichloro
4,5-DICHLOROCATECHOL
4,5-dichloroguaiacol
1,2-Benzenediol,4,5-dichloro
1,2-Benzenediol, 4,5-dichloro-
4,5-Dichloropyrocatechol
4,5-Dichloro-1,2-benzenediol
EINECS 222-331-1
MFCD00463757
4,5-dichlorobenzene-1,2-diol

4,5-二氯儿茶酚生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 其他 >> 其他

[参考文献]

[1]. T Potrawfke , et al. Chlorocatechols Substituted at Positions 4 and 5 Are Substrates of the Broad-Spectrum Chlorocatechol 1,2-dioxygenase of Pseudomonas Chlororaphis RW71. J Bacteriol. 2001 Feb;183(3):997-1011.

4,5-二氯儿茶酚物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
302.2±37.0 °C at 760 mmHg

[ 熔点 ]:
110-115ºC(lit.)

[ 分子式 ]:
C₆H₄Cl₂O₂

[ 分子量 ]:
179.001

[ 闪点 ]:
136.6±26.5 °C

[ 精确质量 ]:
177.958832

[ PSA ]:
40.46000

[ LogP ]:
3.29

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.642

[ 储存条件 ]:
-20°C

4,5-二氯儿茶酚MSDS

4,5-二氯儿茶酚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UX1510000

CHEMICAL NAME :: Pyrocatechol, 4,5-dichloro-

CAS REGISTRY NUMBER :: 3428-24-8

BEILSTEIN REFERENCE NO. :: 2086136

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H4-Cl2-O2

MOLECULAR WEIGHT :: 179.00

WISWESSER LINE NOTATION :: QR BQ DG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 75 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 119,273,1983

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4,5-二氯儿茶酚安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335-H400

[ 警示性声明 ]:
P261-P273-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S26;S36

[ 危险品运输编码 ]:
UN 3077 9 / PGIII

[ RTECS号 ]:
UX1510000

[ 海关编码 ]:
2908199090

4,5-二氯儿茶酚合成路线

4,5-二氯儿茶酚上下游产品

4,5-二氯儿茶酚上游产品

4,5-二氯儿茶酚下游产品

4,5-二氯儿茶酚海关

[ 海关编码 ]: 2908199090

[ 中文概述 ]:
HS:2908199090 其他酚及酚醇的仅含卤素取代基的衍生物及其盐增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

4,5-二氯儿茶酚文献

Oxidation of catechols during positive ion electrospray mass spectrometric analysis: evidence for in-source oxidative dimerization.

Rapid Commun. Mass Spectrom. 28(20) , 2181-90, (2014)

Catechols are an important class of analytes occurring in many natural and synthetic products. Electrospray ionization in negative mode is the preferred way of ion generation for these compounds; howe...

Ormosil gels doped with engineered catechol 1,2 dioxygenases for chlorocatechol bioremediation.

Biotechnol. Appl. Biochem. 61(3) , 297-303, (2014)

Enzymes entrapped in wet, nanoporous silica gel have great potential as bioreactors for bioremediation because of their improved thermal, chemical, and mechanical stability with respect to enzymes in ...

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