1,4-Dichloro-2,3-epoxybutane

DATA ITEMS CITED :

11

MOLECULAR FORMULA :

C4-H6-Cl2-O

MOLECULAR WEIGHT :

141.00

WISWESSER LINE NOTATION :

T3OTJ B1G C1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Open irritation test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

710 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

2830 uL/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :

Insect - Drosophila melanogaster

DOSE/DURATION :

3600 umol/L/3D (Intermittent)

REFERENCE :

35WYAM "In Vitro Metabolic Activation in Mutagenic Testing, Proceedings of the Symposium, Research Triangle Park, NC, 1976," De Serres, F.J., et al., eds., New York, Elsevier Science Pub. Co., Inc., 1976 Volume(issue)/page/year: -,63,1976