N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE

N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE用途

正丁基-DL-同型半胱氨酸硫内酯是一种N-酰基高丝氨酸内酯(AHL)类似物。正丁基-DL-同型半胱氨酸硫内酯对细菌具有潜在的不良影响和毒性。AHL是生物膜形成和毒性因子的有效抑制剂,已用于降解微生物群落,降低细菌致病性[1][2]。

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N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE名称

[ CAS 号 ]:
39837-08-6

[ 英文名 ]:
N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE

[英文别名 ]:

N-Butyryl-DL-homocysteine thiolactone
N-butyryl-L-Homocysteine thiolactone

N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Khalilzadeh P, et al. Growth inhibition of adherent Pseudomonas aeruginosa by an N-butanoyl-L-homoserine lactone analog. Can J Microbiol. 2010 Apr;56(4):317-25.

[2]. Iyer R, et al. Synthetic analogs of bacterial quorum sensors: US, US20110053890[P]. 2011-03-03.

N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE物理化学性质

[ 分子式 ]:
C₈H₁₃NO₂S

[ 分子量 ]:
187.25900

[ 精确质量 ]:
187.06700

[ PSA ]:
74.96000

[ LogP ]:
1.77510

N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONEMSDS

详细MSDS(安全技术说明书)

N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
UN 3335

[ 海关编码 ]:
2934999090

N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE文献

Anticonvulsive effect of folic acid in homocysteine thiolactone-induced seizures.

Cell. Mol. Neurobiol. 31 , 1221-1228, (2011)

Numerous studies have linked folate deficiency and resultant elevated plasma homocysteine levels with an increased risk of neurodegenerative diseases and seizures. The aim of the present study was to ...

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones.

Microbiology 143 , 3703, (1997)

Quorum sensing relies upon the interaction of a diffusible signal molecule with a transcriptional activator protein to couple gene expression with cell population density. In Gram-negative bacteria, s...

[Effect of thiolactone homocysteine loading on adenosine metabolism in rats: relationship with platelet hyper-reactivity, correction of this metabolism disorders by vitamin-microelement complex].

Ukr. Biokhim. Zh. 82 , 59-66, (2010)

Influence of DL-homocysteine thiolactone loading (100 mg/kg by intragastric administration for 28 days) on enzymes activity of adenylic nucleotide and adenosine metabolism in the blood serum, platelet...

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