反式-橙花叔醇

反式-橙花叔醇用途

反式Nerolidol是一种倍半萜醇。它可以从Warionia saharae ex Benth的空中部分分离出来。反式Nerolidol改善了多柔比星(HY-15142A)对体外肠癌细胞的抗增殖作用。反式Nerolidol还具有抗真菌活性[1][2]。

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反式-橙花叔醇名称

[ CAS 号 ]:
40716-66-3

[ 中文名 ]:
反式-橙花叔醇

[ 英文名 ]:
(±)-trans-Nerolidol

[英文别名 ]:

EINECS 255-053-4
±-trans-Nerolidol
1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-, (6E)-
Nerolidol, E-
(6E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol
Nerolidol trans-form
Peruviol
(6E)-Nerolidol
10,11-Dihydronerolidol
Nerolidol, trans

反式-橙花叔醇生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

研究领域 >> 感染

信号通路 >> 抗感染 >> 真菌

[参考文献]

[1]. Hanušová V, et al. The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice. Biomed Pharmacother. 2017 Nov;95:828-836.

[2]. Chan WK, et al. Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities. Molecules. 2016 Apr 28;21(5):529.

反式-橙花叔醇物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
276.0±0.0 °C at 760 mmHg

[ 分子式 ]:
C₁₅H₂₆O

[ 分子量 ]:
222.366

[ 闪点 ]:
96.1±0.0 °C

[ 精确质量 ]:
222.198364

[ PSA ]:
20.23000

[ LogP ]:
5.32

[ 外观性状 ]:
油状物体

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.480

[ 储存条件 ]:
?20°C

反式-橙花叔醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ 海关编码 ]:
2905290000

反式-橙花叔醇合成路线

详细合成路线

反式-橙花叔醇上下游产品

反式-橙花叔醇上游产品

反式-橙花叔醇下游产品

反式-橙花叔醇制备

1. 烟草：FC，18；采用芳樟醇为原料，先将芳樟醇转化为香叶基丙酮，炔化后成为脱氢橙花叔醇，经加氢后即成为橙花叔醇。

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反式-橙花叔醇海关

[ 海关编码 ]: 2905290000

[ 中文概述 ]:
2905290000 其他不饱和一元醇。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

反式-橙花叔醇文献

Phytochemical analysis and in vitro biological activity of three Hypericum species from the Canary Islands (Hypericum reflexum, Hypericum canariense and Hypericum grandifolium).

Fitoterapia 100 , 95-109, (2015)

In the present work we carried out a phytochemical and biological investigation on three Hypericum species, i.e. Hypericum reflexum, Hypericum canariense and Hypericum grandifolium, from the Canary Is...

[Analyze on chemical compositions of Dalbergia odorifera essential oils extracted by CO2-supercritical-fluid-extraction and steam distillation extraction].

Zhong Yao Cai 34(11) , 1725-7, (2011)

To analyze the chemical compositions of Dalbergia odorifera essential oils extacted by CO2-supercritical-fluid-extraction (SFE-CO2) and steam distillation extraction (SD).The essential oils of Dalberg...

Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo.

Fitoterapia 83(5) , 954-60, (2012)

Evodiamine (EVO) and rutaecapine (RUT), the major active components from Evodia rutaecarpa extract (EE), are recognized as a depended analgesic agent. This study was designed to investigate the effect...

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