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MADAM二盐酸盐

MADAM二盐酸盐名称

[ CAS 号 ]:
411208-45-2

[ 中文名 ]:
MADAM二盐酸盐

[ 英文名 ]:
2-[2-[(dimethylamino)methyl]phenyl]sulfanyl-5-methylaniline,dihydrochloride

[英文别名 ]:

dihydrochloride
MADAM dihydrochloride

MADAM二盐酸盐物理化学性质

[ 沸点 ]:
426.4ºC at 760 mmHg

[ 分子式 ]:
C₁₆H₂₂Cl₂N₂S

[ 分子量 ]:
345.33000

[ 闪点 ]:
211.7ºC

[ 精确质量 ]:
344.08800

[ PSA ]:
54.56000

[ LogP ]:
5.97520

MADAM二盐酸盐MSDS

MADAM二盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2930909090

MADAM二盐酸盐合成路线

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MADAM二盐酸盐海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

MADAM二盐酸盐文献

Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.

J. Med. Chem. 45 , 1253-1258, (2002)

A series of diphenyl sulfide derivatives substituted at the 1-, 2'-, and 4'-positions has been synthesized and evaluated for their in vitro affinities at the dopamine, serotonin (SERT), and norepineph...

Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.

J. Pharmacol. Exp. Ther. 304 , 81-87, (2003)

Serotonin transporter has a key-role in regulation of serotoninergic function, and is involved in numerous neurodegenerative and psychiatric disorders. To obtain an efficient radioactive ligand allowi...

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