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邻苯二甲酸单甲酯

邻苯二甲酸单甲酯用途

Monomethyl phthalate 是一种邻苯二甲酸代谢物 (metabolite)。Monomethyl phthalate 作为暴露于 phthalate 后的尿液生物标记物,可作为甲状腺癌和良性结节的检测指标。

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邻苯二甲酸单甲酯名称

[ CAS 号 ]:
4376-18-5

[ 中文名 ]:
邻苯二甲酸单甲酯

[ 英文名 ]:
Monomethyl phthalate

[中文别名 ]:

[英文别名 ]:

1,2-Benzenedicarboxylic acid, monomethyl ester
Phthalic acid methyl ester
2-methoxycarbonylbenzoic acid
2-(Methoxycarbonyl)benzoic acid
Monomethyl phthalate
METHYL HYDROGEN PHTHALATE
phthalic acid, mono-methyl ester
MFCD00002466
1,2-Benzenedicarboxylic acid monomethyl ester
EINECS 224-476-6

邻苯二甲酸单甲酯生物活性

[ 描述 ]:

Monomethyl phthalate 是一种邻苯二甲酸代谢物 (metabolite)。Monomethyl phthalate 作为暴露于 phthalate 后的尿液生物标记物,可作为甲状腺癌和良性结节的检测指标。

[ 相关类别 ]:

研究领域 >> 癌症

[参考文献]

[1]. Chong Liu, et al. Urinary biomarkers of phthalates exposure and risks of thyroid cancer and benign nodule. J Hazard Mater. 2020 Feb 5;383:121189.

邻苯二甲酸单甲酯物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
328.9±25.0 °C at 760 mmHg

[ 熔点 ]:
82-84 °C(lit.)

[ 分子式 ]:
C₉H₈O₄

[ 分子量 ]:
180.157

[ 闪点 ]:
134.7±16.7 °C

[ 精确质量 ]:
180.042252

[ PSA ]:
63.60000

[ LogP ]:
1.13

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.556

[ 储存条件 ]:
Refrigerator

邻苯二甲酸单甲酯MSDS

邻苯二甲酸单甲酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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邻苯二甲酸单甲酯文献

Feasibility of ultra-high performance liquid and gas chromatography coupled to mass spectrometry for accurate determination of primary and secondary phthalate metabolites in urine samples.

Anal. Chim. Acta 853 , 625-36, (2014)

Phthalates (PAEs) are ubiquitous toxic chemical compounds. During the last few years, some phthalate metabolites (MPAEs) have been proposed as appropriate biomarkers in human urine samples to determin...

Monitoring of PAEMs and beta-agonists in urine for a small group of experimental subjects and PAEs and beta-agonists in drinking water consumed by the same subjects.

J. Hazard. Mater. 277 , 169-79, (2014)

This 5-month study contains two parts: (1) to monitor the concentrations of 11 phthalate esters metabolites (PAEMs) and two beta-agonists in human urine samples collected from a small group of consent...

Phthalate Metabolites in Urine Samples from School Children in Taipei, Taiwan.

Arch. Environ. Contam. Toxicol. 69 , 202-7, (2015)

In 2011, Taiwan authorities reported that two phthalates, including di-(2-ethylhexyl) phthalate and di-iso-nonyl phthalate, were intentionally introduced into a variety of foods and beverages during t...

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