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4-差向脱水四环素

4-差向脱水四环素用途

4-表脱水四环素盐酸盐是抗生素四环素的降解产物。4-表脱水四环素盐酸盐对假单胞菌、农杆菌、莫拉菌、芽孢杆菌和大肠杆菌(MIC50s=0.75-16mg/L)具有活性。

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4-差向脱水四环素名称

[ CAS 号 ]:
4465-65-0

[ 中文名 ]:
4-差向脱水四环素盐酸盐

[ 英文名 ]:
4-Epianhydrotetracycline hydrochloride

[中文别名 ]:

[英文别名 ]:

4-Epianhydrotetracycline HCl
MFCD00151455
4-Epi-Anhydrotetracycline Hydrochloride
4-Epianhydrotetracycline hydrochloride

4-差向脱水四环素生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

4-差向脱水四环素物理化学性质

[ 沸点 ]:
618.6ºC at 760 mmHg

[ 熔点 ]:
220ºC

[ 分子式 ]:
C₂₂H₂₃ClN₂O₇

[ 分子量 ]:
462.88000

[ 闪点 ]:
327.9ºC

[ 精确质量 ]:
462.11900

[ PSA ]:
161.39000

[ LogP ]:
1.95810

[ 外观性状 ]:
Powder | Orange

[ 储存条件 ]:
-20?C Freezer

4-差向脱水四环素MSDS

4-差向脱水四环素安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
63-36-22

[ 安全声明 (欧洲) ]:
36/37/39-26

[ 危险品运输编码 ]:
NONH for all modes of transport

4-差向脱水四环素合成路线

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4-差向脱水四环素文献

Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing.

Bioorg. Med. Chem. Lett. 22 , 1709-11, (2012)

Over-expressions of miRNAs are being increasingly linked with many diseases including different types of cancer. In this study, the role of some known small molecular therapeutics has been investigate...

Development of a repressible mycobacterial promoter system based on two transcriptional repressors.

Nucleic Acids Res. 38(12) , e134, (2010)

Tightly regulated gene expression systems represent invaluable tools for studying gene function and for the validation of drug targets in bacteria. While several regulated bacterial promoters have bee...

[A precise equilibrium equation for four steps of binding between TBP and TATA-box allows for the prediction of phenotypical expression upon mutation].

Biofizika 55(3) , 400-14, (2010)

Among the main events of transcription initiation of TATA-containing genes in eukayotes are the recognition and binding of the TATA-box by the TATA-binding protein (TBP) to start the preinitiation com...

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