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甜菊醇

甜菊醇用途

Steviol 是甜菊糖甙的主要代谢物。Steviol 通过降低 AQP2 的表达和促进 AQP2 的降解以减缓肾囊肿的生长。

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甜菊醇名称

[ CAS 号 ]:
471-80-7

[ 中文名 ]:
甜叶菊甙元

[ 英文名 ]:
Steviol

[中文别名 ]:

[英文别名 ]:

steviol
Stevioside
Hydroxydehydrostevic acid
Steviol hydrate

甜菊醇生物活性

[ 描述 ]:

Steviol 是甜菊糖甙的主要代谢物。Steviol 通过降低 AQP2 的表达和促进 AQP2 的降解以减缓肾囊肿的生长。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Noitem R, et al. Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation. Biomed Pharmacother. 2018 May;101:754-762.

甜菊醇物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
464.5±45.0 °C at 760 mmHg

[ 熔点 ]:
215°

[ 分子式 ]:
C₂₀H₃₀O₃

[ 分子量 ]:
318.450

[ 闪点 ]:
248.8±25.2 °C

[ 精确质量 ]:
318.219482

[ PSA ]:
57.53000

[ LogP ]:
4.44

[ 蒸汽压 ]:
0.0±2.6 mmHg at 25°C

[ 折射率 ]:
1.569

[ 储存条件 ]:
2-8C

甜菊醇MSDS

详细MSDS(安全技术说明书)

甜菊醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NZ8176000

CHEMICAL NAME :: Kaur-16-en-18-oic acid, 13-hydroxy-

CAS REGISTRY NUMBER :: 471-80-7

LAST UPDATED :: 199410

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H30-O3

MOLECULAR WEIGHT :: 318.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 gm/L

REFERENCE :: PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 82,2478,1985

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甜菊醇安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
NZ8176000

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甜菊醇下游产品

甜菊醇文献

High-performance thin-layer chromatography analysis of steviol glycosides in Stevia formulations and sugar-free food products, and benchmarking with (ultra) high-performance liquid chromatography.

J. Chromatogr. A. 1350 , 102-11, (2014)

A high-performance TLC (HPTLC) method was newly developed and validated for analysis of 7 steviol glycosides in 6 different types of food and Stevia formulations. After a minimized one-step sample pre...

Preparation and chromatographic evaluation of a newly designed steviol glycoside modified-silica stationary phase in hydrophilic interaction liquid chromatography and reversed phase liquid chromatography.

J. Chromatogr. A. 1388 , 110-8, (2015)

A diterpene glycoside compound, rebaudioside A (commonly abbreviated as RA), was immobilized onto porous silica surface through "thiol-ene" click chemistry strategy. The successful immobilization of t...

Determination of eight artificial sweeteners and common Stevia rebaudiana glycosides in non-alcoholic and alcoholic beverages by reversed-phase liquid chromatography coupled with tandem mass spectrometry.

Anal. Bioanal. Chem 407(5) , 1505-12, (2015)

The method for the determination of acesulfame-K, saccharine, cyclamate, aspartame, sucralose, alitame, neohesperidin dihydrochalcone, neotame and five common steviol glycosides (rebaudioside A, rebau...

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甜菊醇