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β-桉叶醇

β-桉叶醇用途

Beta-Eudesmol 是一种天然的含氧倍半萜烯,可活化 hTRPA1,EC50 值为 32.5 μM。Beta-Eudesmol 可通过 hTRPA1 增加食欲。

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β-桉叶醇名称

[ CAS 号 ]:
473-15-4

[ 中文名 ]:
beta-桉叶醇

[ 英文名 ]:
beta-Eudesmol

[中文别名 ]:

[英文别名 ]:

Eudesm-4(14)-en-11-ol
b-Eudesmol
Eudesmol. B.
beta-eudesmol
(+)-b-Eudesmol
|A-Eudesmol
Eudesm-4(14)-en-11-ol (8CI)
b-Selinenol

β-桉叶醇生物活性

[ 描述 ]:

Beta-Eudesmol 是一种天然的含氧倍半萜烯,可活化 hTRPA1,EC50 值为 32.5 μM。Beta-Eudesmol 可通过 hTRPA1 增加食欲。

[ 相关类别 ]:

信号通路 >> 跨膜转运 >> TRP频道

研究领域 >> 代谢疾病

[参考文献]

[1]. Ohara K, et al. β-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous system. Sci Rep. 2017 Nov 17;7(1):15785.

[2]. Ohara K, et al. Identification of significant amino acids in multiple transmembrane domains of human transient receptor potential ankyrin 1 (TRPA1) for activation by eudesmol, an oxygenized sesquiterpene in hop essential oil. J Biol Chem. 2015 Jan 30;290(5):3161-71.

β-桉叶醇物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
301.7±11.0 °C at 760 mmHg

[ 熔点 ]:
72-74ºC

[ 分子式 ]:
C₁₅H₂₆O

[ 分子量 ]:
222.366

[ 闪点 ]:
108.6±15.6 °C

[ 精确质量 ]:
222.198364

[ PSA ]:
20.23000

[ LogP ]:
4.68

[ 外观性状 ]:
粉末

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.499

[ 储存条件 ]:
2-8°C

β-桉叶醇MSDS

详细MSDS(安全技术说明书)

β-桉叶醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ9698500

CHEMICAL NAME :: 2-Naphthalenemethanol, decahydro-8-methylene-alpha,alpha,4a-trimethyl-, (2R-(2-alpha,4a- alpha,8a-beta)-

CAS REGISTRY NUMBER :: 473-15-4

LAST UPDATED :: 199703

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H26-O

MOLECULAR WEIGHT :: 222.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #92-13629

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β-桉叶醇安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
QJ9698500

β-桉叶醇文献

Aroma evaluation of gamazumi (Viburnum dilatatum) by aroma extract dilution analysis and odour activity value.

Phytochem. Anal. 23(3) , 208-13, (2012)

Viburnum dilatatum (gamazumi) is widely distributed in Japan and China. Recently, juice from V. dilatatum fruits has been manufactured in Japan. Concerning the aroma of V. dilatatum, phenethyl alcohol...

Essential oil composition of Teucrium scordium L.

Acta. Pharm. 57(4) , 499-504, (2007)

Composition of the essential oil obtained from dried flowering aerial parts of Teucrium scordium L. (Labiatae) was analyzed by GC and GC/MS. Fifty-six components were identified in the essential oil o...

Composition and antimicrobial and anti-wood-decay fungal activities of the leaf essential oils of Machilus pseudolongifolia from Taiwan.

Nat. Prod. Commun. 5(7) , 1143-6, (2010)

The hydrodistillated leaf essential oil of Machilus pseudolongifolia was analyzed to determine its composition and yield. Seventy compounds were identified, the main components being beta-eudesmol (26...

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