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1,4-二氯酞嗪

1,4-二氯酞嗪用途

用作医药中间体。

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1,4-二氯酞嗪名称

[ CAS 号 ]:
4752-10-7

[ 中文名 ]:
1,4-二氯酞嗪

[ 英文名 ]:
1,4-Dichlorophthalazine

[中文别名 ]:

[英文别名 ]:

1,4-dichlorophtalazine
MFCD00006909
EINECS 225-275-6
1,4-dichloronaphthazine
1,2-dichlorophthalazine
Phthalazine, 1,4-dichloro-
Phthalazine,1,4-dichloro
1,4-Dichlorophthalazine

1,4-二氯酞嗪物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
397.3±22.0 °C at 760 mmHg

[ 熔点 ]:
160-162 °C(lit.)

[ 分子式 ]:
C₈H₄Cl₂N₂

[ 分子量 ]:
199.037

[ 闪点 ]:
226.4±7.9 °C

[ 精确质量 ]:
197.975159

[ PSA ]:
25.78000

[ LogP ]:
2.13

[ 外观性状 ]:
白色至黄褐色的粉末,晶体,结晶粉末和/或大块

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.671

[ 储存条件 ]:
?20°C

1,4-二氯酞嗪MSDS

1,4-二氯酞嗪安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933990090

1,4-二氯酞嗪合成路线

1,4-二氯酞嗪上下游产品

1,4-二氯酞嗪上游产品

1,4-二氯酞嗪下游产品

1,4-二氯酞嗪海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1,4-二氯酞嗪文献

Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors.

J. Med. Chem. 50 , 3627, (2007)

A series of exceptionally potent agonists at neuronal nicotinic acetylcholine receptors (nAChRs) has been investigated. Several N-(3-pyridinyl) derivatives of bridged bicyclic diamines exhibit double-...

Arylphthalazines. Part 2: 1-(Isoquinolin-5-yl)-4-arylamino phthalazines as potent inhibitors of VEGF receptors I and II.

Bioorg. Med. Chem. Lett. 16 , 1579, (2006)

A novel class of 1-(isoquinolin-5-yl)-4-arylamino-phthalazines is described as inhibitors of vascular endothelial growth factor receptor II (VEGFR-2). Many compounds display VEGFR-2 inhibitory activit...

Discrimination of reactively-dyed cotton fibres with thin layer chromatography and UV microspectrophotometry.

Sci. Justice 55 , 422-30, (2015)

Reactively-dyed black, navy blue and medium red cotton samples showing metamerism under fluorescent tube illumination were examined. Optical microscopy (bright field, polarization and fluorescence mic...

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