1,2-环己二胺四乙酸

1,2-环己二胺四乙酸用途

1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) 是一种螯合剂。1,2-Cyclohexylenedinitrilotetraacetic acid 能够去除经硫酸锰预处理的大鼠脑部和肝脏(体内)及其亚细胞部分(体外)中的锰。

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1,2-环己二胺四乙酸名称

[ CAS 号 ]:
482-54-2

[ 中文名 ]:
1,2-环己二胺四乙酸

[ 英文名 ]:
1,2-Cyclohexylenedinitrilotetraacetic acid

[中文别名 ]:

1,2-环己二胺四乙酸(CDTA)

[英文别名 ]:

idranal iv
EINECS 207-582-7
complexoniv
chel600
1,2-diaminocyclohexane-N,N,N'N'-tetraacetatic acid
octa
TitriplexIV
1,2-diaminocyclohexane-N,N,N',N'-tetraacetic acid
komplexoniv
1,2-cyclohexanediamine-N,N,N',N'-tetraacetic acid

1,2-环己二胺四乙酸生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Tandon SK, et al. Removal of manganese by chelating agents from brain and liver of manganese treated rats: as in vitro and an in vivo study. Toxicology. 1975 Nov;5(2):237-41.

1,2-环己二胺四乙酸物理化学性质

[ 密度 ]:
1.48g/cm3

[ 沸点 ]:
375.4ºC at 760 mmHg

[ 熔点 ]:
210-220°C

[ 分子式 ]:
C₁₄H₂₄N₂O₉

[ 分子量 ]:
364.34800

[ 精确质量 ]:
364.14800

[ PSA ]:
164.91000

[ 外观性状 ]:
白色至白色，带有深黄色铸造粉末

[ 蒸汽压 ]:
1.9E-18mmHg at 25°C

[ 储存条件 ]:
室温

1,2-环己二胺四乙酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AG5000000

CHEMICAL NAME :: Acetic acid, (1,2-cyclohexylenedinitrilo)tetra-

CAS REGISTRY NUMBER :: 482-54-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C14-H22-N2-O8

MOLECULAR WEIGHT :: 346.38

WISWESSER LINE NOTATION :: L6TJ AN1VQ1VQ BN1VQ1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 413 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - aggression Lungs, Thorax, or Respiration - chronic pulmonary edema

REFERENCE :: TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 32,37,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7406 No. of Facilities: 223 (estimated) No. of Industries: 5 No. of Occupations: 4 No. of Employees: 1008 (estimated) No. of Female Employees: 155 (estimated)

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1,2-环己二胺四乙酸安全信息

[ 危害码 (欧洲) ]:
Xi

[ 海关编码 ]:
2922499990

1,2-环己二胺四乙酸合成路线

详细合成路线

1,2-环己二胺四乙酸上下游产品

1,2-环己二胺四乙酸上游产品

1,2-环己二胺四乙酸下游产品

1,2-环己二胺四乙酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%