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蒜糖醇

蒜糖醇用途

Allitol 是一种罕见的天然多元醇,可作为甜味剂。Allitol 是制备 azasugars 的重要中间体,用于制备抗糖尿病、癌症和包括艾滋病在内的病毒感染的药物。

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蒜糖醇名称

[ CAS 号 ]:
488-44-8

[ 中文名 ]:
蒜糖醇

[ 英文名 ]:
D-Sorbitol

[英文别名 ]:

D-Sorbitol
galactitol
L-Allitol
D-Allitol
(2R,3R,4S,5S)-Hexane-1,2,3,4,5,6-hexaol
Allitol
sorbitol

蒜糖醇生物活性

[ 描述 ]:

Allitol 是一种罕见的天然多元醇,可作为甜味剂。Allitol 是制备 azasugars 的重要中间体,用于制备抗糖尿病、癌症和包括艾滋病在内的病毒感染的药物。

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Zhu Y, et al. Construction of allitol synthesis pathway by multi-enzyme coexpression in Escherichia coli and its application in allitol production. J Ind Microbiol Biotechnol. 2015 May;42(5):661-9.

蒜糖醇物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
494.9±0.0 °C at 760 mmHg

[ 熔点 ]:
152 °C

[ 分子式 ]:
C₆H₁₄O₆

[ 分子量 ]:
182.172

[ 闪点 ]:
292.5±23.3 °C

[ 精确质量 ]:
182.079041

[ PSA ]:
121.38000

[ LogP ]:
-4.67

[ 蒸汽压 ]:
0.0±2.8 mmHg at 25°C

[ 折射率 ]:
1.597

[ 储存条件 ]:
2~8°C

蒜糖醇安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
BA1840000

蒜糖醇文献

Efficient conversion of allitol to D-psicose by Bacillus pallidus Y25.

J. Biosci. Bioeng. 103 , 282-285, (2007)

An efficient method for conversion of allitol to D-psicose was achieved by a resting cell reaction of Bacillus pallidus Y25 for the first time. Notably, it was possible to produce D-allose and D-altro...

Possibility as monosaccharide laxative of rare sugar alcohols.

Yakugaku Zasshi 129 , 575-580, (2009)

Allitol, D-talitol and L-iditol are sugar alcohols that are rare in nature. Due to their previous rarity, little is known about the laxative effects of these rare sugar alcohols. Therefore, reliable d...

Identification and quantification of the osmodiuretic mannitol in urine for sports drug testing using gas chromatography-mass spectrometry. Guddat S, Thevis M, Schänzer W.

Eur. J. Mass Spectrom. 14 , 127-133, (2008)

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蒜糖醇