百里醌

Thymoquinone 是从 N. sativa 中分离得到的天然产物。Thymoquinone 具有抗氧化、抗炎、抗癌、抗肿瘤活性和保肝作用。

[ 描述 ]:

[ 相关类别 ]:

[参考文献]

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
232.0±15.0 °C at 760 mmHg

[ 熔点 ]:
167 ºC

[ 分子式 ]:
C₁₀H₁₂O₂

[ 分子量 ]:
164.201

[ 闪点 ]:
103.9±0.0 °C

[ 精确质量 ]:
164.083725

[ PSA ]:
34.14000

[ LogP ]:
2.33

[ 外观性状 ]:
固体;Light yellow to Brown powder to crystal

[ 蒸汽压 ]:
0.1±0.5 mmHg at 25°C

[ 折射率 ]:
1.505

[ 储存条件 ]:
2~8°C

[ 水溶解性 ]:
Very slightly soluble (0.82 g/L) (25 ºC)

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

GU5330000

CHEMICAL NAME :

2,5-Cyclohexadiene-1,4-dione, 2-methyl-5-(1-methylethyl)-

CAS REGISTRY NUMBER :

490-91-5

BEILSTEIN REFERENCE NO. :

1939047

LAST UPDATED :

199701

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C10-H12-O2

MOLECULAR WEIGHT :

164.22

WISWESSER LINE NOTATION :

L6V DVJ B1 EY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

10 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :

Mutation in microorganisms

TEST SYSTEM :

Bacteria - Salmonella typhimurium

DOSE/DURATION :

20 nmol/plate

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 347,37,1995

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
GU5330000

[ 海关编码 ]:
2914690090

百里醌上游产品

百里醌下游产品

暂无

[ 海关编码 ]: 2914690090

[ 中文概述 ]:
2914690090 其他醌. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%

[ Summary ]:
2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Thymoquinone Pretreatment Overcomes the Insensitivity and Potentiates the Antitumor Effect of Gemcitabine Through Abrogation of Notch1, PI3K/Akt/mTOR Regulated Signaling Pathways in Pancreatic Cancer.

Dig. Dis. Sci. 60 , 1067-80, (2015)

The gemcitabine-insensitivity remains the main challenge for pancreatic cancer treatment. Thymoquinone, the predominant bioactive ingredient of Nigella sativa, has been shown to possess promising anti...

Thymoquinone restores radiation-induced TGF-β expression and abrogates EMT in chemoradiotherapy of breast cancer cells.

J. Cell Physiol. 230(3) , 620-9, (2015)

Radiotherapy remains a prime approach to adjuvant therapies in patients with early and advanced breast cancer. In spite of therapeutic success, metastatic progression in patients undergoing therapy, l...

Evaluation of Antioxidant and Antibacterial Potentials of Nigella sativa L. Suspension Cultures under Elicitation.

Biomed Res. Int. 2015 , 708691, (2015)

Nigella sativa L. (family Ranunculaceae) is an annual herb of immense medicinal properties because of its major active components (i.e., thymoquinone (TQ), thymohydroquinone (THQ), and thymol (THY)). ...

更多文献

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：百里醌

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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥588.0/100mg

联系人：刘佳

产品详情：百里醌

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公司名：上海源溪生物科技有限公司

区域：上海市浦东新区

价格：
￥需询单/1g

联系人：赖经理

产品详情：Thymoquinone

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公司名：上海脉铂医药科技有限公司

区域：上海市嘉定区

价格：
￥418.0/1g ￥314.0/500mg ￥1458.0/5g ￥需询单/1g

联系人：李先生

产品详情：Thymoquinone

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥726.9/25g ￥363.9/10g ￥194.9/5g ￥81.9/1g

联系人：阿拉丁

产品详情：百里醌

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