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鸡蛋花甙

鸡蛋花甙用途

Plumieride 是一种抗真菌剂。Plumieride 对一些皮肤真菌有很强的毒性。Plumieride 对 P388 白血病细胞株具有微弱的细胞毒活性,其 IC50 为 85 μg/mL。

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鸡蛋花甙名称

[ CAS 号 ]:
511-89-7

[ 中文名 ]:
鸡蛋花甙

[ 英文名 ]:
Agoniadin

[英文别名 ]:

Agoniadin
Plumieride

鸡蛋花甙生物活性

[ 描述 ]:

Plumieride 是一种抗真菌剂。Plumieride 对一些皮肤真菌有很强的毒性。Plumieride 对 P388 白血病细胞株具有微弱的细胞毒活性,其 IC50 为 85 μg/mL。

[ 相关类别 ]:

研究领域 >> 癌症

研究领域 >> 感染

信号通路 >> 抗感染 >> 真菌

[参考文献]

[1]. Tiwari TN, et al. Plumieride from Allamanda cathartica as an antidermatophytic agent. Phytother Res. 2002 Jun;16(4):393-4.

鸡蛋花甙物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
771.4±60.0 °C at 760 mmHg

[ 熔点 ]:
156-158°; mp 224-225°

[ 分子式 ]:
C₂₁H₂₆O₁₂

[ 分子量 ]:
470.42

[ 闪点 ]:
269.2±26.4 °C

[ 精确质量 ]:
470.142426

[ PSA ]:
181.44000

[ LogP ]:
-4.23

[ 外观性状 ]:
粉末

[ 蒸汽压 ]:
0.0±6.0 mmHg at 25°C

[ 折射率 ]:
1.645

[ 储存条件 ]:
-20℃，密封，干燥

鸡蛋花甙MSDS

详细MSDS(安全技术说明书)

鸡蛋花甙安全信息

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

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鸡蛋花甙文献

Assessment of the genotoxic and mutagenic properties of Himatanthus articulatus bark extracts used as phytotherapeutic drug in the Amazon.

J. Ethnopharmacol. 147(2) , 474-80, (2013)

Himatanthus articulatus (Apocynaceae) is a plant native to the Amazon, popularly used to treat external ulcers, tumors, inflammations, cancer, syphilis and malaria.To investigate the in vivo genotoxic...

Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus fallax from the Suriname rainforest.

J. Nat. Prod. 60(12) , 1294-7, (1997)

Bioassay-guided fractionation of the EtOAc extract of both Allamanda cathartica and Himatanthus fallax (Apocynaceae) using the Sc-7 yeast strain resulted in the isolation of the weakly cytotoxic isopl...

Structural modifications of plumieride isolated from Plumeria bicolor and the effect of these modifications on in vitro anticancer activity.

J. Org. Chem. 69(19) , 6165-72, (2004)

Plumieride was isolated as one of the major components from the biologically active methanolic extract of the bark of Plumeria bicolor (family Apocynaceae). For investigating the effect of substituent...

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