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2,6-二-O-甲基-β-环糊精

2,6-二-O-甲基-β-环糊精用途

2,6-二-O-甲基-β-环糊精是一种生物化学试剂,可作为生物材料或有机化合物进行生命科学相关研究。

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2,6-二-O-甲基-β-环糊精名称

[ CAS 号 ]:
51166-71-3

[ 中文名 ]:
二甲基环糊精

[ 英文名 ]:
Heptakis(2,6-di-O-methyl)-b-cyclodextrin

[中文别名 ]:

[英文别名 ]:

2,6-Di-O-methyl-β-cyclodextrin
Dimethyl β-cyclodextrin
Heptakis(2,6-di-O-methyl)-b-cyclodextrin
MFCD00011616

2,6-二-O-甲基-β-环糊精生物活性

[ 描述 ]:

2,6-二-O-甲基-β-环糊精是一种生物化学试剂,可作为生物材料或有机化合物进行生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

2,6-二-O-甲基-β-环糊精物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
1203.6±65.0 °C at 760 mmHg

[ 熔点 ]:
298 - 310ºC

[ 分子式 ]:
C₅₆H₉₈O₃₅

[ 分子量 ]:
1331.356

[ 闪点 ]:
681.7±34.3 °C

[ 精确质量 ]:
1330.588867

[ PSA ]:
400.05000

[ LogP ]:
6.96

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.553

[ 储存条件 ]:
Refrigerator

[ 水溶解性 ]:
H2O: soluble

2,6-二-O-甲基-β-环糊精MSDS

2,6-二-O-甲基-β-环糊精毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU2293500

CHEMICAL NAME :: beta-Cyclodextrin, 2(sup A),2(sup B),2(sup C),2(sup D),2(sup E),2(sup F),2(sup G),6(sup A),6 (sup B),6(sup C),6(sup D),6(sup E),6(sup F),6(sup G)-tetradeca-O-methyl-

CAS REGISTRY NUMBER :: 51166-71-3

LAST UPDATED :: 199406

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C56-H98-O35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOIPDF Journal of Inclusion Phenomena. (D. Reidel Publishing Co., c/o Kluwer Academic Publishers, P.O. Box 322, 3300 AH Dordrecht, Netherlands) V.1- 1983- Volume(issue)/page/year: 1,135,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 220 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOIPDF Journal of Inclusion Phenomena. (D. Reidel Publishing Co., c/o Kluwer Academic Publishers, P.O. Box 322, 3300 AH Dordrecht, Netherlands) V.1- 1983- Volume(issue)/page/year: 1,135,1983

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOIPDF Journal of Inclusion Phenomena. (D. Reidel Publishing Co., c/o Kluwer Academic Publishers, P.O. Box 322, 3300 AH Dordrecht, Netherlands) V.1- 1983- Volume(issue)/page/year: 1,135,1983

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOIPDF Journal of Inclusion Phenomena. (D. Reidel Publishing Co., c/o Kluwer Academic Publishers, P.O. Box 322, 3300 AH Dordrecht, Netherlands) V.1- 1983- Volume(issue)/page/year: 1,135,1983

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2,6-二-O-甲基-β-环糊精安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
GU2293500

[ 海关编码 ]:
29400090

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2,6-二-O-甲基-β-环糊精文献

Evaluation of the separation mechanism of electrokinetic chromatography with a microemulsion and cyclodextrins using NMR and molecular modeling.

Electrophoresis 32(21) , 3062-9, (2011)

Electrokinetic chromatography (EKC) allows the separation of closely related substances by the detection of fine effects in analyte-separation system interactions. With the goal of understanding the f...

Synthesis, cytotoxicity, and phase-solubility study of cyclodextrin click clusters.

J. Pharm. Sci. 103(10) , 3183-9, (2014)

To explore the possibility of cyclodextrin click clusters (CCCs) as a new cyclodextrin-based excipient, we prepared three different CCCs; heptakis{6-(4-hydroxymethyl-1H-[1,2,3]triazol-1-yl)-6-deoxy}-β...

Host-guest interaction between new nitrooxoisoaporphine and β-cyclodextrins: synthesis, electrochemical, electron spin resonance and molecular modeling studies.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 102 , 226-34, (2013)

A new nitrooxoisoaporphine derivative was synthetized and characterized by cyclic voltammetry and electron spin resonance. Its aqueous solubility was improved by complexes formation with β-cyclodextri...

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