柠檬醛
柠檬醛用途
柠檬醛名称
[ CAS 号 ]:
5392-40-5
[ 中文名 ]:
柠檬醛
[ 英文名 ]:
Citral
[中文别名 ]:
[英文别名 ]:
- Lemsyn GB
- 3,7-Dimethyl-1,2,6-octadienal
- LEMAROME
- 2,6-octadienal, 3,7-dimethyl-
- (2E)-3,7-Dimethyl-2,6-octadienal
- NERAL
- gerznial
- lemsyngb
- 3,7-Dimethylocta-2,6-dienal
- 3,7-dimethyl-2,6-octadien-1-al
柠檬醛生物活性
柠檬醛物理化学性质
[ 密度 ]:
0.9±0.1 g/cm3
[ 沸点 ]:
229.0±9.0 °C at 760 mmHg
[ 熔点 ]:
< -10ºC
[ 分子式 ]:
C10H16O
[ 分子量 ]:
152.233
[ 闪点 ]:
101.7±0.0 °C
[ 精确质量 ]:
152.120117
[ PSA ]:
17.07000
[ LogP ]:
3.17
[ 外观性状 ]:
透明至淡黄色油性液体
[ 蒸汽密度 ]:
5 (vs air)
[ 蒸汽压 ]:
0.1±0.5 mmHg at 25°C
[ 折射率 ]:
1.457
[ 储存条件 ]:
2-8°C
[ 稳定性 ]:
Stable. but readily isomerizes. Incompatible with alkalies, strong oxidizing agents, strong acids. Combustible. Air and light sensitive.
[ 水溶解性 ]:
PRACTICALLY INSOLUBLE
柠檬醛MSDS
柠檬醛毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RG5075000
- CHEMICAL NAME :
- 2,6-Octadienal, 3,7-dimethyl-
- CAS REGISTRY NUMBER :
- 5392-40-5
- BEILSTEIN REFERENCE NO. :
- 1721871
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 30
- MOLECULAR FORMULA :
- C10-H16-O
- MOLECULAR WEIGHT :
- 152.26
- WISWESSER LINE NOTATION :
- VH1UY1&3Y1&U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Human
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Human - man
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Mammal - pig
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4960 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 460 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6 gm/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 24 gm/kg/10D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Effect on specific coenzyme - CoA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14952 mg/kg/14D-I
- TOXIC EFFECTS :
- Liver - other changes Liver - changes in liver weight Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1250 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2500 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 10 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 10 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Effects on Newborn - sex ratio
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 28 gm/kg
- SEX/DURATION :
- female 60 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - oogenesis Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 46 gm/kg
- SEX/DURATION :
- female 14 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 46 gm/kg
- SEX/DURATION :
- female 14 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Fertility - other measures of fertility Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 27600 mg/kg
- SEX/DURATION :
- female 60 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - live birth index (measured after birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 1800 mg/kg
- SEX/DURATION :
- female 22 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - oogenesis Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 1800 mg/kg
- SEX/DURATION :
- female 6 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Effects on Newborn - live birth index (measured after birth)
MUTATION DATA
- TYPE OF TEST :
- DNA repair
- TEST SYSTEM :
- Bacteria - Bacillus subtilis
- DOSE/DURATION :
- 2222 ug/disc
- REFERENCE :
- OIGZDE Osaka-shi Igakkai Zasshi. Journal of Osaka City Medical Association. (Osaka-shi Igakkai, c/o Osaka-shiritsu Daigaku Igakubu, 1-4-54 Asahi-cho, Abeno-ku, Osaka, 545, Japan) V.24- 1975- Volume(issue)/page/year: 34,267,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83184 No. of Facilities: 353 (estimated) No. of Industries: 5 No. of Occupations: 33 No. of Employees: 68051 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83184 No. of Facilities: 12505 (estimated) No. of Industries: 98 No. of Occupations: 84 No. of Employees: 200484 (estimated) No. of Female Employees: 83180 (estimated)
柠檬醛安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H315-H317-H319
[ 警示性声明 ]:
P280-P305 + P351 + P338
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xi:Irritant;
[ 风险声明 (欧洲) ]:
R38;R43
[ 安全声明 (欧洲) ]:
S24/25-S37
[ 危险品运输编码 ]:
1760
[ WGK德国 ]:
1
[ RTECS号 ]:
RG5075000
[ 包装等级 ]:
III
[ 危险类别 ]:
8
[ 海关编码 ]:
2932999099
柠檬醛合成路线
柠檬醛上下游产品
柠檬醛上游产品
柠檬醛下游产品
柠檬醛制备
1.柠檬醛主要存在于山苍子油、柠檬草油、桉叶油、柠檬罗勒油、柠檬艾油和柑橘油中。主要是从这些精油中分离而得，也可以通过香叶醇和橙花醇的氧化制取。
山苍子等去杂粉碎蒸馏↓水蒸气分离
精油精馏粗产品精制↓NaHSO3产品
2. 以甲基庚烯酮为原料合成。甲基庚烯酮与乙氧基乙炔溴化镁缩合生成炔醇，经还原反应成烯醇醚，后者用磷酸水解和脱水而生成柠檬醛。
3.制法：
于压力容弹（高压釜）中加入香叶醇（2）1.42g（10mol），二苯酮1.82g（10mmol），双环戊二烯二氢锆（Cp2ZrH2）0.2mmol，氩气保护。于130℃反应6h。滤去催化剂，硅胶柱纯化，得化合物①（1），收率92%。注：①采用类似方法可以合成如下各种化合物（表I-7-1）。
柠檬醛海关
[ 海关编码 ]: 2912190090
[ 中文概述 ]:
HS: 2912190090. 其他无环醛（不含其他含氧基）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 四聚甲醛报明外观
[ Summary ]:
2912190090 acyclic aldehydes without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
柠檬醛文献
Phytochemistry 104 , 12-20, (2014)
Studies on the biosynthesis of oil compounds in Perilla will help in understanding regulatory systems of secondary metabolites and in elucidating reaction mechanisms for natural product synthesis. In ...
Heterogeneous nucleation and shape transformation of multicomponent metallic nanostructures.Nat. Mater. 14(2) , 215-23, (2015)
To be able to control the functions of engineered multicomponent nanomaterials, a detailed understanding of heterogeneous nucleation at the nanoscale is essential. Here, by using in situ synchrotron X...
Effect of citral on the cytotoxicity of doxorubicin in human B-lymphoma cells.Pharm. Biol. 53(2) , 262-8, (2015)
Doxorubicin is a chemotherapy agent used in non-Hodgkin's lymphoma but side effects limit its use. Citral is a mixture of neral and geranial found in essential oils of lemon grass.We evaluated the act...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：柠檬醛
公司名：南通润丰石油化工有限公司
区域：南通市崇川区
价格：
￥需询单/1kg
￥需询单/1ton
联系人：曹经理
产品详情：柠檬醛
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥348.0/500ml
￥108.0/100ml
联系人：刘佳
产品详情：柠檬醛
公司名：上海脉铂医药科技有限公司
区域：上海市嘉定区
价格：
￥588.89/100mg
联系人：李先生
产品详情：柠檬醛
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥46.0/25ml
￥94.0/100ml
￥284.0/500ml
￥1026.0/2500ml
联系人：夏言
产品详情：[Perfemiker]柠檬醛,97%，顺式 + 反式
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相关化合物
【柠檬醛】化源网提供柠檬醛CAS号5392-40-5，柠檬醛MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询柠檬醛上化源网，专业又轻松。>>电脑版：柠檬醛
标题：柠檬醛_MSDS_用途_密度_柠檬醛CAS号【5392-40-5】_化源网 地址：https://m.chemsrc.com/mip/cas/5392-40-5_1027907.html