5β-胆烷酸
5β-胆烷酸用途
5β-胆烷酸名称
[ CAS 号 ]:
546-18-9
[ 中文名 ]:
5β-胆烷酸
[ 英文名 ]:
5β-cholanoic acid
[中文别名 ]:
[英文别名 ]:
- (5β)-Cholan-24-oic acid
- 5b-Cholan-24-oic Acid
- 5beta-Cholanoic acid
- Cholan-24-oic acid, (5β)-
- Ursocholanic acid
- 5beta-Cholan-24-oic acid
- 5β-cholan-24-oic acid
- 5β-cholanic acid
- MFCD00065904
- Cholanoic acid
5β-胆烷酸生物活性
5β-胆烷酸物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
473.6±13.0 °C at 760 mmHg
[ 分子式 ]:
C24H40O2
[ 分子量 ]:
360.573
[ 闪点 ]:
208.7±11.2 °C
[ 精确质量 ]:
360.302826
[ PSA ]:
37.30000
[ LogP ]:
8.75
[ 外观性状 ]:
固体
[ 蒸汽压 ]:
0.0±2.5 mmHg at 25°C
[ 折射率 ]:
1.514
[ 储存条件 ]:
室温
5β-胆烷酸安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危险品运输编码 ]:
NONH for all modes of transport
5β-胆烷酸文献
Steroids 58(2) , 52-8, (1993)
An efficient method for the preparation of 4 beta- and 6 alpha-hydroxylated bile acids has been developed. It involved a highly stereoselective acetoxylation at the 4 beta and 6 alpha positions of 3- ...
Calcium- and voltage-gated potassium (BK) channel activators in the 5β-cholanic acid-3α-ol analogue series with modifications in the lateral chain.ChemMedChem 7(10) , 1784-92, (2012)
Large conductance, calcium- and voltage-gated potassium (BK) channels regulate various physiological processes and represent an attractive target for drug discovery. Numerous BK channel activators are...
Cholanic acids determined in commercial drugs by means of a new ISFET device.J. Pharm. Biomed. Anal. 11(11-12) , 1207-14, (1993)
An ISFET device selective for cholanic acids, based on a PVC-sebacate membrane, containing benzyldimethylcetylammoniumcholate as exchanger, has been prepared, characterized and applied to the determin...
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