5β-胆烷酸

5β-胆烷酸用途

5β-胆酸可用于5β-胆酸衍生物的合成[1]。

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5β-胆烷酸名称

[ CAS 号 ]:
546-18-9

[ 中文名 ]:
5β-胆烷酸

[ 英文名 ]:
5β-cholanoic acid

[中文别名 ]:

5B-胆烷酸

[英文别名 ]:

(5β)-Cholan-24-oic acid
5b-Cholan-24-oic Acid
5beta-Cholanoic acid
Cholan-24-oic acid, (5β)-
Ursocholanic acid
5beta-Cholan-24-oic acid
5β-cholan-24-oic acid
5β-cholanic acid
MFCD00065904
Cholanoic acid

5β-胆烷酸生物活性

[ 描述 ]:

5β-胆酸可用于5β-胆酸衍生物的合成[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Weizhi Wang, et al. Improved oral delivery of insulin by PLGA nanoparticles coated with 5 β-cholanic acid conjugated glycol chitosan. Biomed Mater. 2021 Oct 12;16(6).

5β-胆烷酸物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
473.6±13.0 °C at 760 mmHg

[ 分子式 ]:
C₂₄H₄₀O₂

[ 分子量 ]:
360.573

[ 闪点 ]:
208.7±11.2 °C

[ 精确质量 ]:
360.302826

[ PSA ]:
37.30000

[ LogP ]:
8.75

[ 外观性状 ]:
固体

[ 蒸汽压 ]:
0.0±2.5 mmHg at 25°C

[ 折射率 ]:
1.514

[ 储存条件 ]:
室温

5β-胆烷酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

5β-胆烷酸文献

An efficient synthesis of 4 beta- and 6 alpha-hydroxylated bile acids.

Steroids 58(2) , 52-8, (1993)

An efficient method for the preparation of 4 beta- and 6 alpha-hydroxylated bile acids has been developed. It involved a highly stereoselective acetoxylation at the 4 beta and 6 alpha positions of 3- ...

Calcium- and voltage-gated potassium (BK) channel activators in the 5β-cholanic acid-3α-ol analogue series with modifications in the lateral chain.

ChemMedChem 7(10) , 1784-92, (2012)

Large conductance, calcium- and voltage-gated potassium (BK) channels regulate various physiological processes and represent an attractive target for drug discovery. Numerous BK channel activators are...

Cholanic acids determined in commercial drugs by means of a new ISFET device.

J. Pharm. Biomed. Anal. 11(11-12) , 1207-14, (1993)

An ISFET device selective for cholanic acids, based on a PVC-sebacate membrane, containing benzyldimethylcetylammoniumcholate as exchanger, has been prepared, characterized and applied to the determin...

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