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异雌三醇

异雌三醇用途

16表雌三醇是内源性雌激素雌酮的代谢产物,具有抗菌和抗炎作用[1][2][3]。

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异雌三醇名称

[ CAS 号 ]:
547-81-9

[ 中文名 ]:
表雌三醇

[ 英文名 ]:
16-Epiestriol

[中文别名 ]:

[英文别名 ]:

16-EPISTRIOL
Epiestriol
16-epioestriol
Actriol
Estriol (3,16.β.,17.β.)
16beta-hydroxyestradiol
16b,17b-Estriol
EPIESTRIOL,16
16-EPIESTRIOL
Epioestriol

异雌三醇生物活性

[ 描述 ]:

16表雌三醇是内源性雌激素雌酮的代谢产物,具有抗菌和抗炎作用[1][2][3]。

[ 相关类别 ]:

研究领域 >> 感染

研究领域 >> 炎症/免疫

[参考文献]

[1]. Brinton LA, et al. Serum Estrogens and Estrogen Metabolites and Endometrial Cancer Risk among Postmenopausal Women. Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1081-9.

[2]. Skariyachan S, et al. Natural epiestriol-16 act as potential lead molecule against prospective molecular targets of multidrug resistant Acinetobacter baumannii-Insight from in silico modelling and in vitro investigations. Infect Genet Evol. 2020 Aug;82:104314.

[3]. Latman NS, et al. 16-epiestriol: an anti-inflammatory steroid without glycogenic activity. J Pharm Sci. 1994 Jun;83(6):874-7.

异雌三醇物理化学性质

[ 密度 ]:
1.255g/cm3

[ 沸点 ]:
469ºC at 760 mmHg

[ 熔点 ]:
289-291ºC

[ 分子式 ]:
C₁₈H₂₄O₃

[ 分子量 ]:
288.38100

[ 闪点 ]:
220.8ºC

[ 精确质量 ]:
288.17300

[ PSA ]:
60.69000

[ LogP ]:
2.58000

[ 折射率 ]:
1.624

[ 储存条件 ]:
-20°C

异雌三醇安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

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异雌三醇文献

Associations of the fecal microbiome with urinary estrogens and estrogen metabolites in postmenopausal women.

J. Clin. Endocrinol. Metab. 99(12) , 4632-40, (2014)

The gut microbiota may influence the risk of breast cancer through effects on endogenous estrogens.The objective of the study was to investigate whether urinary estrogens and estrogen metabolites are ...

Study of urinary steroid hormone disorders: difference between hepatocellular carcinoma in early stage and cirrhosis.

Anal. Bioanal. Chem 406(18) , 4325-35, (2014)

Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Discovery of novel biomarkers for early HCC from other liver diseases such as cirrhosis is of great clinical benefit. In th...

Comparison of metabolic ratios of urinary estrogens between benign and malignant thyroid tumors in postmenopausal women.

BMC Clin. Pathol. 13 , 25, (2014)

Estrogen metabolism may be associated with the pathophysiological development of papillary thyroid carcinoma (PTC).To evaluate the differential estrogen metabolism between benign and malignant PTCs, e...

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