醋酸麦迪霉素

醋酸麦迪霉素用途

Miocamycin (Midecamycin acetate) 是一种 midecamycin (HY-B1908) 的衍生物。Miocamycin 具有抗菌特性。
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醋酸麦迪霉素名称

[ CAS 号 ]:
55881-07-7

[ 中文名 ]:
醋酸麦迪霉素

[ 英文名 ]:
Midecamycin acetate

[中文别名 ]:

[英文别名 ]:

醋酸麦迪霉素生物活性

[ 描述 ]:

Miocamycin (Midecamycin acetate) 是一种 midecamycin (HY-B1908) 的衍生物。Miocamycin 具有抗菌特性。

[ 相关类别 ]:

研究领域 >> 感染
信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. TOXICOLOGICAL STUDIES ON A NEW MACROLIDE ANTIBIOTIC, MIDECAMYCIN ACETATE (MIOCAMYCIN). July 1984. Volume 37 Issue 7 Pages 1355-1375.

醋酸麦迪霉素物理化学性质

[ 密度 ]:
1.2 g/cm3

[ 沸点 ]:
878.7ºC at 760 mmHg

[ 熔点 ]:
~220° (with coloration)

[ 分子式 ]:
C45H71NO17

[ 分子量 ]:
898.04200

[ 闪点 ]:
485.2ºC

[ 精确质量 ]:
897.47200

[ PSA ]:
218.19000

[ LogP ]:
3.90900

[ 外观性状 ]:
白色或灰白色结晶粉末

[ 折射率 ]:
1.524

醋酸麦迪霉素毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OH4730020
CHEMICAL NAME :
Leucomycin V, 3(sup B),9-diacetate 3,4(sup B)-dipropanoate
CAS REGISTRY NUMBER :
55881-07-7
LAST UPDATED :
199806
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C45-H71-N-O17
MOLECULAR WEIGHT :
898.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,1331,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1313,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984
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