醋酸麦迪霉素
醋酸麦迪霉素用途
醋酸麦迪霉素名称
[ CAS 号 ]:
55881-07-7
[ 中文名 ]:
醋酸麦迪霉素
[ 英文名 ]:
Midecamycin acetate
[中文别名 ]:
[英文别名 ]:
- Acecamycin
- 9,3''-di-O-acetylmidecamycin
- Ponsinomycin
- Mom
- 9,3''-diacetylmidecamycin
- Miocamycin
- Miokamycin
- 3',9-Diacetylmydecamycin
醋酸麦迪霉素生物活性
醋酸麦迪霉素物理化学性质
[ 密度 ]:
1.2 g/cm3
[ 沸点 ]:
878.7ºC at 760 mmHg
[ 熔点 ]:
~220° (with coloration)
[ 分子式 ]:
C45H71NO17
[ 分子量 ]:
898.04200
[ 闪点 ]:
485.2ºC
[ 精确质量 ]:
897.47200
[ PSA ]:
218.19000
[ LogP ]:
3.90900
[ 外观性状 ]:
白色或灰白色结晶粉末
[ 折射率 ]:
1.524
醋酸麦迪霉素毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OH4730020
- CHEMICAL NAME :
- Leucomycin V, 3(sup B),9-diacetate 3,4(sup B)-dipropanoate
- CAS REGISTRY NUMBER :
- 55881-07-7
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C45-H71-N-O17
- MOLECULAR WEIGHT :
- 898.17
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,1331,1995
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1313,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984
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