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孔雀石绿

孔雀石绿用途

碱性绿4(孔雀石绿)是一种阳离子染料。碱性绿4也是一种用于着色的N-甲基化二氨基三苯基甲烷染料[1]。

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孔雀石绿名称

[ CAS 号 ]:
569-64-2

[ 中文名 ]:
孔雀绿

[ 英文名 ]:
Malachite green

[中文别名 ]:

[英文别名 ]:

China Green
Benzal Green
Malachite green chloride
Malachite Green ; Basic Green 4
Grenoble Green
Aniline Green
Victoria Green B
Basic Green 4
Victoria Green
Diamond Green B

孔雀石绿生物活性

[ 描述 ]:

碱性绿4(孔雀石绿)是一种阳离子染料。碱性绿4也是一种用于着色的N-甲基化二氨基三苯基甲烷染料[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Chowdhury. S, et al. Sea shell powder as a new adsorbent to remove Basic Green 4 (Malachite Green) from aqueous solutions: Equilibrium, kinetic and thermodynamic studies. Chemical Engineering Journal, 164(1), 168–177.

孔雀石绿物理化学性质

[ 密度 ]:
1.0448 (rough estimate)

[ 沸点 ]:
520.91°C (rough estimate)

[ 熔点 ]:
158-160ºC

[ 分子式 ]:
C₂₃H₂₅ClN₂

[ 分子量 ]:
364.911

[ 精确质量 ]:
364.170624

[ PSA ]:
6.25000

[ LogP ]:
1.39760

[ 外观性状 ]:
绿色晶体

[ 折射率 ]:
1.5940 (estimate)

[ 储存条件 ]:
Refrigerator

[ 水溶解性 ]:
Solubility Very soluble in water; soluble in ethanol, methanol, amyl alcohol

孔雀石绿MSDS

孔雀石绿毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BQ1180000

CHEMICAL NAME :: Ammonium, (4-(p-(dimethylamino)-alpha-phenylbenzylidene)-2,5-cy clohexadien-1-ylidene )- dimethyl-, chloride

CAS REGISTRY NUMBER :: 569-64-2

LAST UPDATED :: 199712

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C23-H25-N2.Cl

MOLECULAR WEIGHT :: 364.95

WISWESSER LINE NOTATION :: L6Y DYJ AUYR&R DN1&1& DUK1&1 &Q &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 10 pph

REFERENCE :: BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 11,2537,1972 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84620 No. of Facilities: 2852 (estimated) No. of Industries: 25 No. of Occupations: 47 No. of Employees: 28485 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84620 No. of Facilities: 5859 (estimated) No. of Industries: 84 No. of Occupations: 65 No. of Employees: 181763 (estimated) No. of Female Employees: 18135 (estimated)

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孔雀石绿安全信息

[ 符号 ]:

GHS05, GHS07, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H318-H361d-H410

[ 警示性声明 ]:
P273-P280-P305 + P351 + P338-P501

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn;N

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
BQ1190000

[ 包装等级 ]:
III

[ 海关编码 ]:
29215900

孔雀石绿合成路线

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孔雀石绿文献

Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium.

Oncogene 33(50) , 5688-96, (2014)

Phosphatase and tensin homolog (PTEN) is one of the most frequently mutated tumor suppressor genes in cancers. PTEN has a central role in phosphatidylinositol (3,4,5)-trisphosphate (PIP3) signaling an...

Dimethyl sulphoxide and Ca2+ stimulate assembly of Vibrio cholerae FtsZ.

Biochimie 105 , 64-75, (2014)

We cloned, overexpressed and purified Vibrio cholerae FtsZ protein for the first time. We used several complementary techniques to probe and compare the comparative assembly properties of recombinant ...

Specific interaction with cardiolipin triggers functional activation of Dynamin-Related Protein 1.

PLoS ONE 9(7) , e102738, (2014)

Dynamin-Related Protein 1 (Drp1), a large GTPase of the dynamin superfamily, is required for mitochondrial fission in healthy and apoptotic cells. Drp1 activation is a complex process that involves tr...

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