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1-L-酪氨酸生长抑素

1-L-酪氨酸生长抑素用途

[Tyr1]-Somatostatin-14 可结合到生长激素抑制素受体 SSTR2。

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1-L-酪氨酸生长抑素名称

[ CAS 号 ]:
59481-23-1

[ 中文名 ]:
1-L-酪氨酸生长抑素

[ 英文名 ]:
[Tyr1]-Somatostatin-14

[英文别名 ]:

(TYR1)-SOMATOSTATIN-14
1-L-Tyrosinesomatostatin (sheep)
YGCKNFFWKTFTSC(Disulfidebridge:3-14)

1-L-酪氨酸生长抑素生物活性

[ 描述 ]:

[Tyr1]-Somatostatin-14 可结合到生长激素抑制素受体 SSTR2。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 生长抑素受体

研究领域 >> 内分泌

[参考文献]

[1]. S Kagimoto, et al. Human somatostatin receptor, SSTR2, is coupled to adenylyl cyclase in the presence of Gi alpha 1 protein. Biochem Biophys Res Commun. 1994 Jul 29;202(2):1188-95.

1-L-酪氨酸生长抑素物理化学性质

[ 分子式 ]:
C₈₂H₁₀₈N₁₈O₂₀S₂

[ 分子量 ]:
1729.97000

[ 精确质量 ]:
1728.74000

[ PSA ]:
684.06000

[ LogP ]:
3.21460

1-L-酪氨酸生长抑素MSDS

详细MSDS(安全技术说明书)

1-L-酪氨酸生长抑素安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

1-L-酪氨酸生长抑素文献

Effect of Deletion of Ghrelin-O-Acyltransferase on the Pulsatile Release of Growth Hormone in Mice.

J. Neuroendocrinol. 27 , 872-86, (2015)

Ghrelin, a gut hormone originating from the post-translational cleavage of preproghrelin, is the endogenous ligand of growth hormone secretagogue receptor 1a (GHS-R1a). Within the growth hormone (GH) ...

Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.

Sci. Signal. 8 , ra113, (2015)

Skeletal muscle is the largest organ, comprising 40% of the total body lean mass, and affects whole-body metabolism in multiple ways. We investigated the signaling pathways involved in this process us...

Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid.

EMBO J. 34 , 1875-88, (2015)

MT1-MMP (MMP14) is a collagenolytic enzyme located at the cell surface and implicated in extracellular matrix (ECM) remodeling. Mmp14(-/-) mice present dwarfism, bone abnormalities, and premature deat...

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