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氧环唑

氧环唑用途

【用途一】
用于木材防腐

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氧环唑名称

[ CAS 号 ]:
60207-31-0

[ 中文名 ]:
氧环唑

[ 英文名 ]:
Azaconazole

[中文别名 ]:

[英文别名 ]:

AZACONAZOLE
EINECS 262-102-3
Azoconazole
Madurox
MFCD00865600
Azoconozole

氧环唑物理化学性质

[ 密度 ]:
1.51 g/cm3

[ 沸点 ]:
460.7ºC at 760 mmHg

[ 熔点 ]:
112.6ºC

[ 分子式 ]:
C₁₂H₁₁Cl₂N₃O₂

[ 分子量 ]:
300.14100

[ 闪点 ]:
232.4ºC

[ 精确质量 ]:
299.02300

[ PSA ]:
49.17000

[ LogP ]:
2.48470

[ 折射率 ]:
1.658

[ 储存条件 ]:
0-6°C

氧环唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XZ4605000

CHEMICAL NAME :: 1H-1,2,4-Triazole, 1-((2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl)methyl)-

CAS REGISTRY NUMBER :: 60207-31-0

BEILSTEIN REFERENCE NO. :: 0822252

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H11-Cl2-N3-O2

MOLECULAR WEIGHT :: 300.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 308 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,43,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,43,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1123 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,43,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 114 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,43,1991

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氧环唑安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22

[ 安全声明 (欧洲) ]:
S46

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
XZ4605000

氧环唑文献

Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi.

PLoS Pathog. 6 , e1001126, (2010)

Despite the wealth of knowledge regarding the mechanisms of action and the mechanisms of resistance to azole antifungals, very little is known about how the azoles are imported into pathogenic fungal ...

In vivo and in vitro effects of azaconazole on renal function in the Fischer 344 rat.

Toxicology 34(1) , 1-11, (1985)

Azaconazole is an experimental agricultural fungicide which has shown promise for use in controlling powdery mildew on crops and bean rust. This study examined the nephrotoxic potential of a single in...

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氧环唑