五氯苯
五氯苯用途
用途：用于制备五氯硝基苯。
五氯苯名称
[ CAS 号 ]:
608-93-5
[ 中文名 ]:
五氯苯
[ 英文名 ]:
Benzene,1,2,3,4,5-pentachloro-
[英文别名 ]:
- MFCD00000539
- Pentachlorobenzene
- EINECS 210-172-0
五氯苯物理化学性质
[ 密度 ]:
1.609 g/mL at 25 °C(lit.)
[ 沸点 ]:
275-277 °C(lit.)
[ 熔点 ]:
84-87 °C(lit.)
[ 分子式 ]:
C6HCl5
[ 分子量 ]:
250.33700
[ 闪点 ]:
131.6ºC
[ 精确质量 ]:
247.85200
[ LogP ]:
4.95360
[ 折射率 ]:
1.595
[ 储存条件 ]:
0-6°C
五氯苯MSDS
五氯苯毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DA6640000
- CHEMICAL NAME :
- Benzene, pentachloro-
- CAS REGISTRY NUMBER :
- 608-93-5
- BEILSTEIN REFERENCE NO. :
- 1911550
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 18
- MOLECULAR FORMULA :
- C6-H-Cl5
- MOLECULAR WEIGHT :
- 250.32
- WISWESSER LINE NOTATION :
- GR BG CG DG EG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1080 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - tremor
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 4(5-6),183,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 4(5-6),183,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1175 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - tremor
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 4(5-6),183,1980 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1662 mg/kg/28D-C
- TOXIC EFFECTS :
- Liver - changes in liver weight
- REFERENCE :
- JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 11,663,1983
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 248 mg/kg/15D-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-91-3125
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9 gm/kg/26W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in leukocyte (WBC) count
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 4(5-6),183,1980
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1738 mg/kg/13W-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Endocrine - adrenal cortex hyperplasia Blood - other changes
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 119,181,1993
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5940 mg/kg/15D-C
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - tremor Related to Chronic Data - death
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-91-3125
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10909 mg/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
- REFERENCE :
- NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-91-3125 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 5,117,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1802 mg/kg
- SEX/DURATION :
- male 13 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-185983
五氯苯安全信息
[ 符号 ]:
GHS02, GHS07, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H228-H302-H410
[ 警示性声明 ]:
P210-P273-P501
[ 靶器官 ]:
Blood, Central nervous system, Liver
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
F,Xn,N
[ 风险声明 (欧洲) ]:
11-22-50/53-40
[ 安全声明 (欧洲) ]:
S41-S46-S50-S60-S61-S36/37-S24/25-S23
[ 危险品运输编码 ]:
UN 3077 9/PG 3
[ WGK德国 ]:
3
[ RTECS号 ]:
DA6640000
[ 海关编码 ]:
2903999090
五氯苯合成路线
五氯苯上下游产品
五氯苯上游产品
五氯苯下游产品
五氯苯制备
制备方法：由苯或二氯苯、三氯苯氯化制四氯苯时，作为副产物得到。也可由苯深度氯化得到的四氯苯、五氯苯和六氯苯的混合物经精馏、结晶分离得到。
五氯苯海关
[ 海关编码 ]: 2903999090
[ 中文概述 ]:
2903999090 其他芳烃卤化衍生物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
五氯苯文献
Eur. J. Med. Chem. 43 , 714-40, (2008)
Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org...
Determination of chlorobenzenes in water samples by solid-phase disk extraction and gas chromatography-electron capture detection.J. Chromatogr. Sci. 52(5) , 375-82, (2014)
A simple, rapid, sensitive and high throughput method is described, based on solid-phase disk extraction (SPDE) and gas chromatography-electron capture detection, for the determination of chlorobenzen...
Contamination and emission factors of PCDD/Fs, unintentional PCBs, HxCBz, PeCBz and polychlorophenols in chloranil in China.Chemosphere 86(3) , 248-51, (2012)
The production of chloranil is regarded as a potentially significant source of unintentional POPs. This research aimed to identify the contamination levels of polychlorinated dibenzo-p-dioxins and dib...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥348.0/1g
￥1118.0/5g
￥178.0/2ml
联系人：刘佳
产品详情：五氯苯
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥476.0/500mg
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：五氯苯
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相关化合物
【五氯苯】化源网提供五氯苯CAS号608-93-5，五氯苯MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询五氯苯上化源网，专业又轻松。>>电脑版：五氯苯
标题：五氯苯_MSDS_用途_密度_五氯苯CAS号【608-93-5】_化源网 地址：https://m.chemsrc.com/mip/cas/608-93-5_951349.html