3-氨基-1,2-丙二醇
3-氨基-1,2-丙二醇用途
主要用于生产X-CT非离子型造影剂碘海醇、合成特种材料,也用作农药中间体
【用途二】
主要用于生产X-CT非离子型造影剂碘海醇。
3-氨基-1,2-丙二醇名称
[ CAS 号 ]:
616-30-8
[ 中文名 ]:
3-氨基-1,2-丙二醇
[ 英文名 ]:
3-Amino-1,2-propanediol
[中文别名 ]:
[英文别名 ]:
- 1,2-Propanediol, 3-amino-
- 3-Amino-1,2-propanediol
- EINECS 210-475-8
- MFCD00008140
- 3-Amino-1,2-proopanediol
- UNII:RH369P864X
- 3-Aminopropan-1,2-diol
- 3-aminopropane-1,2-diol
3-氨基-1,2-丙二醇物理化学性质
[ 密度 ]:
1.2±0.1 g/cm3
[ 沸点 ]:
266.7±20.0 °C at 760 mmHg
[ 分子式 ]:
C3H9NO2
[ 分子量 ]:
91.109
[ 闪点 ]:
115.1±21.8 °C
[ 精确质量 ]:
91.063332
[ PSA ]:
66.48000
[ LogP ]:
-1.98
[ 外观性状 ]:
黏的透明液体
[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C
[ 折射率 ]:
1.496
[ 储存条件 ]:
库房通风低温干燥
[ 水溶解性 ]:
soluble
3-氨基-1,2-丙二醇MSDS
3-氨基-1,2-丙二醇毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TY2800000
- CHEMICAL NAME :
- 1,2-Propanediol, 3-amino-
- CAS REGISTRY NUMBER :
- 616-30-8
- BEILSTEIN REFERENCE NO. :
- 1719121
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C3-H9-N-O2
- MOLECULAR WEIGHT :
- 91.13
- WISWESSER LINE NOTATION :
- Z1YQ1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SCCUR* Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583) Volume(issue)/page/year: -,1,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2460 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SCCUR* Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583) Volume(issue)/page/year: -,1,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 246 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SCCUR* Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583) Volume(issue)/page/year: -,1,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 198 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SCCUR* Shell Chemical Company. Unpublished Report. (2401 Crow Canyon Rd., San Romon, CA 94583) Volume(issue)/page/year: -,1,1961
3-氨基-1,2-丙二醇安全信息
[ 符号 ]:
GHS05
[ 信号词 ]:
Danger
[ 危害声明 ]:
H314
[ 警示性声明 ]:
P280-P305 + P351 + P338-P310
[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
C:Corrosive
[ 风险声明 (欧洲) ]:
R34
[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45
[ 危险品运输编码 ]:
UN 2735 8/PG 2
[ WGK德国 ]:
2
[ RTECS号 ]:
TY2800000
[ 包装等级 ]:
III
[ 危险类别 ]:
8
[ 海关编码 ]:
2922199090
3-氨基-1,2-丙二醇合成路线
3-氨基-1,2-丙二醇上下游产品
3-氨基-1,2-丙二醇上游产品
3-氨基-1,2-丙二醇下游产品
3-氨基-1,2-丙二醇海关
[ 海关编码 ]: 2922199090
[ 中文概述 ]:
2922199090. 其他氨基醇及其醚,酯和它们的盐(但含一种以上含氧基的除外). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
3-氨基-1,2-丙二醇文献
Nucleic Acids Res. 24(17) , 3357-63, (1996)
Adenine, thymine and cytosine PNA monomers have been prepared using 3-amino-1,2-propanediol as a starting material. The benzoyl group was used to protect the exocyclic amines of the heterocyclic bases...
Competitive inhibition of lipolytic enzymes. II. Preparation of 'monoacylamino' phospholipids.Biochim. Biophys. Acta 1043(1) , 67-74, (1990)
This paper describes the synthesis of a number of phosphatidylcholines and phosphatidylglycols, in which one fatty acyl ester group is replaced by an acylamino function. The phospholipids, both of the...
Three new derivatives of 3-amino-1,2-propanediol; their spectral properties and biological evaluation.Acta Pol. Pharm. 58(4) , 249-56, (2001)
Three new derivatives of 3-amino-1,2-propanediol have been synthesized. Full assignments of signals in their 1H- and 13C-NMR spectra are given. The influence of these compounds on the cardiovascular s...
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