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N-(2-羟乙基)吗啉

N-(2-羟乙基)吗啉用途

【用途一】
用于有机合成。

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N-(2-羟乙基)吗啉名称

[ CAS 号 ]:
622-40-2

[ 中文名 ]:
2-吗啉乙醇

[ 英文名 ]:
2-Morpholinoethanol

[中文别名 ]:

[英文别名 ]:

2-(4-Morpholinyl)ethanol
4-Morpholineethanol
2-Morpholinoethanol
β-Morpholinoethanol
MFCD00006180
EINECS 210-734-5
4-(2-hydroxyethyl)morpholine
2-morpholin-4-ylethanol
2-(morpholin-4-yl)ethanol

N-(2-羟乙基)吗啉物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
224.4±20.0 °C at 760 mmHg

[ 熔点 ]:
-1 °C

[ 分子式 ]:
C₆H₁₃NO₂

[ 分子量 ]:
131.173

[ 闪点 ]:
99.4±0.0 °C

[ 精确质量 ]:
131.094635

[ PSA ]:
32.70000

[ LogP ]:
-0.60

[ 外观性状 ]:
透明无色至黄色液体

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.470

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
miscible

N-(2-羟乙基)吗啉MSDS

N-(2-羟乙基)吗啉毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QE3510000

CHEMICAL NAME :: 4-Morpholineethanol

CAS REGISTRY NUMBER :: 622-40-2

BEILSTEIN REFERENCE NO. :: 0104375

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C6-H13-N-O2

MOLECULAR WEIGHT :: 131.20

WISWESSER LINE NOTATION :: T6N DOTJ A2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5500 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >16 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 1 gm/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 136,153,1984

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N-(2-羟乙基)吗啉安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
QE3510000

[ 海关编码 ]:
29349990

N-(2-羟乙基)吗啉合成路线

N-(2-羟乙基)吗啉上下游产品

N-(2-羟乙基)吗啉上游产品

N-(2-羟乙基)吗啉下游产品

N-(2-羟乙基)吗啉制备

【方法一】
由吗啉与环氧乙烷加成而得。将环氧乙烷气体通入吗啉中反应，温度控制在20℃以下，通毕，保温半小时。加热蒸除水分至尽，残留液减压蒸馏，收集122-126℃（1.33kPa）馏分，得吗啉乙醇。

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N-(2-羟乙基)吗啉海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N-(2-羟乙基)吗啉文献

Impact of the structure of biocompatible aliphatic polycarbonates on siRNA transfection ability.

Biomacromolecules 16(3) , 769-79, (2015)

RNAi therapeutics are promising therapeutic tools that have sparked the interest of many researchers. In an effort to provide a safe alternative to PEI, we have designed a series of new guanidinium- a...

Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes.

Bioorg. Med. Chem. 19 , 5679-92, (2011)

In this work libraries of morpholines and oxazepanes have been prepared via the reductive amination reaction between dialdehydes, derived from carbohydrates, and a range of amines. In this way, functi...

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N-(2-羟乙基)吗啉

N-(2-羟乙基)吗啉用途

N-(2-羟乙基)吗啉名称

N-(2-羟乙基)吗啉物理化学性质

N-(2-羟乙基)吗啉MSDS

详细MSDS(安全技术说明书)

N-(2-羟乙基)吗啉毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

N-(2-羟乙基)吗啉安全信息

N-(2-羟乙基)吗啉合成路线

详细合成路线

N-(2-羟乙基)吗啉上下游产品

N-(2-羟乙基)吗啉上游产品

N-(2-羟乙基)吗啉下游产品

N-(2-羟乙基)吗啉制备

N-(2-羟乙基)吗啉海关

N-(2-羟乙基)吗啉文献

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