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反-戊烯二酸

反-戊烯二酸名称

[ CAS 号 ]:
628-48-8

[ 中文名 ]:
反-戊烯二酸

[ 英文名 ]:
GLUTACONIC ACID

[英文别名 ]:

Glutaconic Acid
(E)-pent-2-enedioic acid
MFCD00002784

反-戊烯二酸物理化学性质

[ 熔点 ]:
137-139ºC(lit.)

[ 分子式 ]:
C₅H₆O₄

[ 分子量 ]:
130.09900

[ 精确质量 ]:
130.02700

[ PSA ]:
74.60000

[ LogP ]:
0.10190

[ 储存条件 ]:
室温，干燥

反-戊烯二酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

反-戊烯二酸合成路线

详细合成路线

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反-戊烯二酸文献

Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme.

Bioorg. Med. Chem. 17 , 5414-9, (2009)

Fumarate, a four-carbon trans dicarboxylic acid, is the allosteric activator of the human mitochondrial NAD(P)(+)-dependent malic enzyme (m-NAD(P)-ME). In this paper, we discuss the effects of the str...

Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids.

Biochem. Biophys. Res. Commun. 272(2) , 431-5, (2000)

We recently reported that acrylic acid (AA) induces the MPT in vitro, which we suggested might be a critical event in the acute inflammatory and hyperplastic response of the olfactory epithelium. The ...

Efficient synthesis and neuroprotective effect of substituted 1,3-diphenyl-2-propen-1-ones.

J. Med. Chem. 51 , 4054-8, (2008)

An efficient synthesis involving a key aldol reaction and biological properties of 1,3-diphenyl-2-propen-1-ones 8- 20 is described. The in vitro activity for 2,2-diphenyl-1-picrylhydrazyl (DPPH) radic...

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