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α-香树脂醇

α-香树脂醇用途

α-氨吡啶是一种五环三萜。α-氨基水杨酸具有持久的抗伤害和抗炎特性。α-氨基吡啶可用于炎症研究[1]。

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α-香树脂醇名称

[ CAS 号 ]:
638-95-9

[ 中文名 ]:
α-香树精

[ 英文名 ]:
alpha-Amyrin

[中文别名 ]:

[英文别名 ]:

α-Amyrenol
12a,14,14a,14b-icosahydropicen-3-ol
a-Amyrenol
Urs-12-en-3b-ol
VIMINALOL
AMYRIN,A
MFCD00016754
α-Amyrin
EINECS 211-352-1
Urs-12-en-3β-ol

α-香树脂醇生物活性

[ 描述 ]:

α-氨吡啶是一种五环三萜。α-氨基水杨酸具有持久的抗伤害和抗炎特性。α-氨基吡啶可用于炎症研究[1]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. J. L. Powers; W. E. Powers (1940). The isolation and identification of alpha- and beta-amyrin from the bark of Viburnum opulus. , 29(4), 175–178.

α-香树脂醇物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
493.8±45.0 °C at 760 mmHg

[ 熔点 ]:
178-183°C

[ 分子式 ]:
C₃₀H₅₀O

[ 分子量 ]:
426.717

[ 闪点 ]:
218.6±21.0 °C

[ 精确质量 ]:
426.386169

[ PSA ]:
20.23000

[ LogP ]:
11.01

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±2.8 mmHg at 25°C

[ 折射率 ]:
1.538

[ 储存条件 ]:
2-8℃

α-香树脂醇MSDS

α-香树脂醇安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

α-香树脂醇合成路线

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α-香树脂醇制备

1. 从乙醇中得针晶。

2. 烟草：FC，8， 41；从马尼拉榄香脂（Manilaelemi）中分离得到。

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α-香树脂醇文献

β-Amyrin biosynthesis: the critical role of steric volume at C-19 of 2,3-oxidosqualene for its correct folding to generate the pentacyclic scaffold.

Org. Lett. 16(13) , 3548-51, (2014)

The effect of the steric volume at C-19 of (3S)-2,3-oxidosqualene 1 on the polycyclization reaction by β-amyrin synthase was examined. The substrate analogs, in which the methyl group at C-19 of 1 was...

Comparative analysis of CYP93E proteins for improved microbial synthesis of plant triterpenoids.

Phytochemistry 108 , 47-56, (2014)

Cytochrome P450-dependent monooxygenases (P450s) belonging to the CYP93E subfamily catalyze the C-24 oxidation of the triterpene backbone during the biosynthesis of triterpenoid saponins, which are bi...

Antitrypanosomal triterpenoid with an ε-lactone E-ring from Salvia urmiensis.

J. Nat. Prod. 76(9) , 1806-9, (2013)

A new triterpenoid, urmiensolide (1), was isolated from Salvia urmiensis. The structure was elucidated by a combination of 1D and 2D NMR, HRESIMS, and X-ray crystallographic analyses. The absolute con...

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