比索洛尔

Bisoprolol 是一种有效的选择性的,具有口服活性的 β1 肾上腺素受体 (β1-adrenergic receptor) 阻滞剂。Bisoprolol 对 β2 受体的活性很小,可用于高血压,冠状动脉疾病和稳定的心室功能障碍的研究。

[ 描述 ]:

[ 相关类别 ]:

[ 靶点 ]

[参考文献]

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
445.0±45.0 °C at 760 mmHg

[ 分子式 ]:
C₁₈H₃₁NO₄

[ 分子量 ]:
325.443

[ 闪点 ]:
222.9±28.7 °C

[ 精确质量 ]:
325.225311

[ PSA ]:
59.95000

[ LogP ]:
2.14

[ 外观性状 ]:
黄色油状

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.500

[ 储存条件 ]:
库房通风低温干燥

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UB8380000

CHEMICAL NAME :

2-Propanol, 1-(4-((2-(1-methylethoxy)ethoxy)methyl)phenoxy)-3-((1 -methylethyl)amino)-

CAS REGISTRY NUMBER :

66722-44-9

LAST UPDATED :

199206

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C18-H31-N-O4

MOLECULAR WEIGHT :

325.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

143 ug/kg

TOXIC EFFECTS :

Cardiac - change in rate

REFERENCE :

HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990- Volume(issue)/page/year: 9,255,1990

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
UB8380000

[ 海关编码 ]:
2922509090

4-[(2-异丙氧基乙氧基)甲基]苯酚和环氧氯丙烷反应，生成的环氧化物再和异丙胺反应，即得比索洛尔。

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

High throughput quantification of prohibited substances in plasma using thin film solid phase microextraction.

J. Chromatogr. A. 1374 , 40-9, (2014)

Simple, fast and efficient sample preparation approaches that allow high-throughput isolation of various compounds from complex matrices are highly desired in bioanalysis. Particularly sought are meth...

Enantiomeric fraction evaluation of pharmaceuticals in environmental matrices by liquid chromatography-tandem mass spectrometry.

J. Chromatogr. A. 1363 , 226-235, (2014)

The interest for environmental fate assessment of chiral pharmaceuticals is increasing and enantioselective analytical methods are mandatory. This study presents an enantioselective analytical method ...

β-Blockers promote angiogenesis in the mouse aortic ring assay.

J. Cardiovasc. Pharmacol. 64(1) , 21-7, (2014)

Recent results indicate that the reduction of β-adrenergic signaling impairs angiogenesis under ischemic conditions. Because angiogenesis may occur in the absence of ischemia, it remains to be determi...

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：比索洛尔

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥793.9/25mg ￥720.9/1ml ￥2059.9/100mg ￥需询单/1g

联系人：阿拉丁

产品详情：比索洛尔

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