多沙唑嗪杂质F

二氢速心律失常是维生素D的合成类似物。二氢速心律失常可用于研究低钙血症(血液中缺乏钙)和甲状旁腺功能减退(体内缺乏甲状旁腺激素)[1][2]。

[ 描述 ]:

[ 相关类别 ]:

[体外研究]

[体内研究]

[参考文献]

[ 密度 ]:
1.003 g/cm3

[ 沸点 ]:
499.5ºC at 760 mmHg

[ 熔点 ]:
131ºC

[ 分子式 ]:
C₂₈H₄₆O

[ 分子量 ]:
398.66400

[ 闪点 ]:
217.6ºC

[ 精确质量 ]:
398.35500

[ PSA ]:
20.23000

[ LogP ]:
7.72090

[ 折射率 ]:
1.569

[ 储存条件 ]:
-20°C

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

WW0600000

CHEMICAL NAME :

Tachysterol, dihydro-

CAS REGISTRY NUMBER :

67-96-9

LAST UPDATED :

199504

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C28-H46-O

MOLECULAR WEIGHT :

398.74

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

288 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,330,1982

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

104 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,330,1982 ** REPRODUCTIVE DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

150 mg/kg

SEX/DURATION :

female 1-5 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :

CUSCAM Current Science. (Current Science Assoc., Sadashivanagar P.O., Bangalore 560 080, India) V.1- 1932- Volume(issue)/page/year: 41,181,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5329 No. of Facilities: 19 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 403 (estimated) No. of Female Employees: 189 (estimated)

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301

[ 警示性声明 ]:
Missing Phrase - N15.00950417

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
22

[ 安全声明 (欧洲) ]:
36

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
WW0600000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

详细合成路线

Prevalence and correction of 25(OH) vitamin D deficiency in peritoneal dialysis patients.

Perit. Dial. Int. 25(4) , 362-6, (2005)

Peritoneal dialysis (PD) patients are at risk for 25(OH) vitamin D deficiency due to effluent loss in addition to traditional risk factors.To measure 25(OH) vitamin D deficiency in prevalent PD patien...

3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells.

Brain Res. Mol. Brain Res. 133(2) , 215-23, (2005)

3-nitropropionic acid (3-NPA), a complex II inhibitor of the electron transport chain, causes Huntington disease-like symptoms after administration into animals. However, primary mechanisms of cell de...

Calpain-mediated AQP2 proteolysis in inner medullary collecting duct.

Biochem. Biophys. Res. Commun. 303(1) , 52-8, (2003)

Vitamin D-elicited hypercalcemia/hypercalciuria is associated with polyuria in humans and in animal models. In rats, dihydrotachysterol (DHT) induces AQP2 water channel downregulation despite unaltere...

更多文献

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐乾明

产品详情：Dihydrotachysterol

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公司名：上海源溪生物科技有限公司

区域：上海市浦东新区

价格：
￥需询单/1g

联系人：赖经理

产品详情：HSDB 3314

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥556.9/10mg ￥991.9/50mg ￥需询单/1g ￥需询单/10g

联系人：阿拉丁

产品详情：Dihydrotachysterol

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