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4-(羟基甲基)苯氧基乙酸

4-(羟基甲基)苯氧基乙酸用途

4-(Hydroxymethyl)phenoxyacetic acid 是一种对酸不稳定的树脂连接剂,用于固相肽合成。

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4-(羟基甲基)苯氧基乙酸名称

[ CAS 号 ]:
68858-21-9

[ 中文名 ]:
4-(羟基甲基)苯氧基乙酸

[ 英文名 ]:
4-(Hydroxymethyl)phenoxyacetic acid

[中文别名 ]:

[英文别名 ]:

HMP Linker
Acetic acid, 2-[4-(hydroxymethyl)phenoxy]-
HMPLinker
2-[4-(hydroxymethyl)phenoxy]acetic acid
[4-(Hydroxymethyl)phenoxy]acetic acid
MFCD00057827
EINECS 229-560-6
HMP-Linker

4-(羟基甲基)苯氧基乙酸生物活性

[ 描述 ]:

4-(Hydroxymethyl)phenoxyacetic acid 是一种对酸不稳定的树脂连接剂,用于固相肽合成。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. C T Bui, et al. Improving the performance of an acid-labile 4-hydroxymethyl phenoxyacetic acid (HMP) linker on resin and SynPhase grafted solid-supports. J Pept Sci. 2000 Oct;6(10):534-8.

4-(羟基甲基)苯氧基乙酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
378.3±22.0 °C at 760 mmHg

[ 熔点 ]:
112-114 °C

[ 分子式 ]:
C₉H₁₀O₄

[ 分子量 ]:
182.173

[ 闪点 ]:
156.3±15.8 °C

[ 精确质量 ]:
182.057907

[ PSA ]:
66.76000

[ LogP ]:
0.16

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.573

[ 储存条件 ]:
2-8°C

4-(羟基甲基)苯氧基乙酸MSDS

4-(羟基甲基)苯氧基乙酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2918990090

4-(羟基甲基)苯氧基乙酸合成路线

4-(羟基甲基)苯氧基乙酸上下游产品

4-(羟基甲基)苯氧基乙酸上游产品

4-(羟基甲基)苯氧基乙酸下游产品

4-(羟基甲基)苯氧基乙酸海关

[ 海关编码 ]: 2918990090

[ 中文概述 ]:
2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

4-(羟基甲基)苯氧基乙酸文献

Acid-labile resin linkage agents for use in solid phase peptide synthesis.

Int. J. Pept. Protein Res. 20(5) , 451-4, (1982)

Details are given of the preparation of two acid-labile peptide-resin linkage agents for use in solid phase peptide synthesis, viz. 4-hydroxymethylphenoxy-acetic acid and 3-methoxy-4-hydroxymethylphen...

Improving the performance of an acid-labile 4-hydroxymethyl phenoxyacetic acid (HMP) linker on resin and SynPhase grafted solid-supports.

J. Pept. Sci. 6(10) , 534-8, (2000)

A replacement of the acetic acid moiety by valeric acid within the 4-hydroxymethylphenoxyacetic acid (HMP) linker (Sheppard RC, Williams BJ. Acid-labile resin linkage agents for use in solid phase pep...

E. Atherton et al.

J. Chem. Soc. Chem. Commun. , 537, (1978)

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