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对氯苯甲酸

对氯苯甲酸用途

【用途一】
用作医药、农药和染料及有机合成中间体
【用途二】
用于有机合成
【用途三】
对氯苯甲酸是杀菌剂烯酰吗啉,杀鼠剂杀鼠灵、杀鼠醚和杀虫剂氟氯苯菊酯的中间体,也是染料和医药的中间体。
【用途四】
染料、农药、医药的中间体。
【用途五】
有机微量分析测定碳、氢、氯的标准样品。
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对氯苯甲酸名称

[ CAS 号 ]:
74-11-3

[ 中文名 ]:
香橙素

[ 英文名 ]:
4-Chlorobenzoic acid

[中文别名 ]:

[英文别名 ]:

对氯苯甲酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
287.2±13.0 °C at 760 mmHg

[ 熔点 ]:
238-241 °C(lit.)

[ 分子式 ]:
C7H5ClO2

[ 分子量 ]:
156.566

[ 闪点 ]:
127.5±19.8 °C

[ 精确质量 ]:
155.997803

[ PSA ]:
37.30000

[ LogP ]:
2.65

[ 外观性状 ]:
白色至灰白色结晶片

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.583

[ 储存条件 ]:
库房低温通风干燥

[ 稳定性 ]:
Stable. Combustible. Incompatible with bases, strong oxidizing agents.

[ 水溶解性 ]:
soluble in hot water

对氯苯甲酸MSDS

对氯苯甲酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG4976010
CHEMICAL NAME :
Benzoic acid, p-chloro-
CAS REGISTRY NUMBER :
74-11-3
BEILSTEIN REFERENCE NO. :
0907196
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C7-H5-Cl-O2
MOLECULAR WEIGHT :
156.57
WISWESSER LINE NOTATION :
QVR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1170 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 21,794,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 112,53,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1170 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 23,724,1975
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对氯苯甲酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P301 + P312 + P330

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
DG4976010

[ 海关编码 ]:
4002191900

对氯苯甲酸上下游产品

对氯苯甲酸制备

其制备方法是将高锰酸钾溶液分次加入对氯甲苯和水的混合物中,在75~90℃搅拌下回流5~6h,反应毕用盐酸酸化至pH=2,过滤得粗品,乙醇重结晶得成品。

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对氯苯甲酸海关

[ 海关编码 ]: 2916399090

[ 中文概述 ]:
2916399090 其他芳香一元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

对氯苯甲酸文献

Kinetics of the esterification of active pharmaceutical ingredients containing carboxylic acid functionality in polyethylene glycol: formulation implications.

J. Pharm. Sci. 103(8) , 2424-33, (2014)

Polyethylene glycols (PEGs) are attractive as excipients in the manufacture of drug products because they are water soluble and poorly immunogenic. They are used in various pharmaceutical preparations...

Enhanced hydroxyl radical generation in the combined ozonation and electrolysis process using carbon nanotubes containing gas diffusion cathode.

Environ. Sci. Pollut. Res. Int. 22 , 15812-20, (2015)

Combination of ozone together with electrolysis (ozone-electrolysis) is a promising wastewater treatment technology. This work investigated the potential use of carbon nanotube (CNT)-based gas diffusi...

Benzenepolycarboxylic acids with potential anti-hemorrhagic properties and structure–activity relationships

Bioorg. Med. Chem. 19 , 7000-2, (2011)

Previously, we reported the structural requirements of the cinnamic acid relatives for inhibition of snake venom hemorrhagic action. In the present study, we examined the effect of benzenepolycarboxyl...


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【对氯苯甲酸】化源网提供对氯苯甲酸CAS号74-11-3,对氯苯甲酸MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询对氯苯甲酸上化源网,专业又轻松。>>电脑版:对氯苯甲酸

标题:对氯苯甲酸_MSDS_用途_密度_对氯苯甲酸CAS号【74-11-3】_化源网 地址:https://m.chemsrc.com/mip/cas/74-11-3_1084285.html