N,N'-二苯基对苯二胺

N,N'-二苯基对苯二胺用途

用于天然丁苯、丁腈、顺丁、丁基、聚异戊二烯等橡胶、胶乳中，可使其具有良好的耐多次挠曲性和防龟裂性能。提高定伸强力，增强对热氧、臭氧以及铜墙铁壁锰等有害金属的防护作用，对硫化无影响。与防老剂Ｄ并用可解决深色橡胶制品的多种老化问题。此外，也用作聚乙稀、聚丙稀?

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N,N'-二苯基对苯二胺名称

[ CAS 号 ]:
74-31-7

[ 中文名 ]:
N,N'-二苯基-1,4-苯二胺

[ 英文名 ]:
1,4-Dianilinobenzene

[中文别名 ]:

[英文别名 ]:

1,4-Benzenediamine, N,N'-diphenyl-
1,4-benzenediamine, N1,N4-diphenyl-
1-N,4-N-diphenylbenzene-1,4-diamine
N,N'-Diphenyl-1,4-benzenediamine
p-phenylenediamine, N,N'-diphenyl-
dppd
N,N'-Diphenyl-1,4-phenylenediamine
n,n'-diphenylbenzene-1,4-diamine
1,4-Benzenediamine, N,N-diphenyl-
N,N′-Diphenyl-1,4-phenylenediamine

N,N'-二苯基对苯二胺物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
469.2±0.0 °C at 760 mmHg

[ 熔点 ]:
143-145 °C(lit.)

[ 分子式 ]:
C₁₈H₁₆N₂

[ 分子量 ]:
260.333

[ 闪点 ]:
297.0±13.0 °C

[ 精确质量 ]:
260.131348

[ PSA ]:
24.06000

[ LogP ]:
3.32

[ 外观性状 ]:
淡灰色至棕色粉末

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.694

[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开储运存放

[ 稳定性 ]:
Stable. Incompatible with strong acids, strong oxidizing agents

[ 水溶解性 ]:
<0.1 g/100 mL at 20 ºC

N,N'-二苯基对苯二胺MSDS

N,N'-二苯基对苯二胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ST2275000

CHEMICAL NAME :: p-Phenylenediamine, N,N'-diphenyl-

CAS REGISTRY NUMBER :: 74-31-7

BEILSTEIN REFERENCE NO. :: 2215944

LAST UPDATED :: 199710

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C18-H16-N2

MOLECULAR WEIGHT :: 260.36

WISWESSER LINE NOTATION :: RMR DMR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2370 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 182 gm/kg/2Y-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20443 mg/kg/3W-C

TOXIC EFFECTS :: Blood - change in clotting factors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1000 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 450 mg/kg

SEX/DURATION :: female 14 day(s) pre-mating female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - stillbirth

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2500 mg/kg

SEX/DURATION :: female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4176 mg/kg

SEX/DURATION :: female 6-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 30 mg/L

REFERENCE :: SWEHDO Scandinavian Journal of Work, Environment and Health. (Haartmaninkatu 1, SF-00290 Helsinki, 29, Finland) V.1- 1975- Volume(issue)/page/year: 9(Suppl 2),27,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80282 No. of Facilities: 315 (estimated) No. of Industries: 5 No. of Occupations: 22 No. of Employees: 7496 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80282 No. of Facilities: 139 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 7680 (estimated)

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N,N'-二苯基对苯二胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H317-H412

[ 警示性声明 ]:
P273-P280

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R43;R52/53

[ 安全声明 (欧洲) ]:
S24-S37-S61

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
ST2275000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2921590090

N,N'-二苯基对苯二胺合成路线

N,N'-二苯基对苯二胺上下游产品

N,N'-二苯基对苯二胺上游产品

N,N'-二苯基对苯二胺下游产品

N,N'-二苯基对苯二胺制备

将对苯二酚与苯胺在磷酸三乙酯的催化下，于280～300℃和0.7MPa的压力下反应一定时间。反应结束后进行真空蒸馏。先在低真空下除去过量的苯胺，然后再在较高的真空下蒸出中间物。将蒸完中间物的剩余物料进行切片、打粉、包装即为成品。合成反应如下

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N,N'-二苯基对苯二胺海关

[ 海关编码 ]: 2921590090

[ 中文概述 ]:
2921590090. 其他芳香多胺及衍生物及它们的盐. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N,N'-二苯基对苯二胺文献

Skin sensitization potency and cross-reactivity of p-phenylenediamine and its derivatives evaluated by non-radioactive murine local lymph node assay and guinea-pig maximization test.

Contact Dermatitis 60(4) , 193-8, (2009)

p-Phenylenediamine (PPD)-related chemicals have been used as antioxidants in rubber products, and many cases of contact dermatitis caused by these chemicals have been reported.The aim of this study wa...

Insight into the mechanism of trypanosome lytic factor-1 killing of Trypanosoma brucei brucei.

Mol. Biochem. Parasitol. 118(1) , 33-40, (2001)

It has been known for almost a century that normal human serum can lyse the extracellular blood parasite Trypanosoma brucei brucei. This process is a result of a non-immune killing factor in human ser...

Antioxidative and apoptotic properties of polyphenolic extracts from edible part of artichoke (Cynara scolymus L.) on cultured rat hepatocytes and on human hepatoma cells.

Nutr. Cancer 60(2) , 276-83, (2008)

Cultured rat hepatocytes and human hepatoma HepG2 cells were used to evaluate the hepatoprotective properties of polyphenolic extracts from the edible part of artichoke (AE). The hepatocytes were expo...

更多文献

N,N'-二苯基对苯二胺

N,N'-二苯基对苯二胺用途

N,N'-二苯基对苯二胺名称

N,N'-二苯基对苯二胺物理化学性质

N,N'-二苯基对苯二胺MSDS

详细MSDS(安全技术说明书)

N,N'-二苯基对苯二胺毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

N,N'-二苯基对苯二胺安全信息

N,N'-二苯基对苯二胺合成路线

详细合成路线

N,N'-二苯基对苯二胺上下游产品

N,N'-二苯基对苯二胺上游产品

N,N'-二苯基对苯二胺下游产品

N,N'-二苯基对苯二胺制备

N,N'-二苯基对苯二胺海关

N,N'-二苯基对苯二胺文献

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