N-甲酰脱乙酰秋水仙碱

N-甲酰脱乙酰秋水仙碱名称

[ CAS 号 ]:
7411-12-3

[ 中文名 ]:
N-甲酰脱乙酰秋水仙碱

[ 英文名 ]:
Formamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

[英文别名 ]:

N-甲酰脱乙酰秋水仙碱物理化学性质

[ 密度 ]:
1.27g/cm3

[ 沸点 ]:
715.8ºC at 760 mmHg

[ 熔点 ]:
264-267ºC

[ 分子式 ]:
C21H23NO6

[ 分子量 ]:
385.41000

[ 闪点 ]:
386.7ºC

[ 精确质量 ]:
385.15300

[ PSA ]:
83.09000

[ LogP ]:
3.50830

[ 折射率 ]:
1.591

N-甲酰脱乙酰秋水仙碱毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GH0794000
CHEMICAL NAME :
Colchicine, N-deacetyl-N-formyl-
CAS REGISTRY NUMBER :
7411-12-3
BEILSTEIN REFERENCE NO. :
2824080
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C21-H23-N-O6
MOLECULAR WEIGHT :
385.45
WISWESSER LINE NOTATION :
L B677 MV&T&J CO1 DO1 EO1 JMVH NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 33,1606,1950
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4400 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,284,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2666 ug/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9200 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,284,1957
点击显示

N-甲酰脱乙酰秋水仙碱安全信息

[ 海关编码 ]:
2924299090

N-甲酰脱乙酰秋水仙碱合成路线

N-甲酰脱乙酰秋水仙碱海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺(包括环氨基甲酸酯)(包括其衍生物以及他们的盐). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

推荐生产厂家/供应商:

暂无推荐供应商。请联系客服获知如何成为推荐供应商。


相关化合物

【N-甲酰脱乙酰秋水仙碱】化源网提供N-甲酰脱乙酰秋水仙碱CAS号7411-12-3,N-甲酰脱乙酰秋水仙碱MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询N-甲酰脱乙酰秋水仙碱上化源网,专业又轻松。>>电脑版:N-甲酰脱乙酰秋水仙碱

标题:N-甲酰脱乙酰秋水仙碱_密度_熔点_沸点_CAS号【7411-12-3】_化源网 地址:https://m.chemsrc.com/mip/cas/7411-12-3_829163.html