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三碘甲烷

三碘甲烷用途

Iodoform is the organoiodine compound with the formula CHI3. A pale yellow, crystalline, volatile substance, it has a penetrating and distinctive odor (in older chemistry texts, the smell is sometimes referred to as the smell of hospitals, where the compound is still commonly used) and, analogous to chloroform, sweetish taste. It is occasionally used as a disinfectant. It is also known as tri-iodomethane, carbon triiodide, and methyl triiodide.
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三碘甲烷作用

【用途一】
在医芭和生物化学中用作防腐剂和消毒剂。小鼠口服LD50为910mg/kg。
【用途二】
生物化学，防腐。
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三碘甲烷名称

[ CAS 号 ]:
75-47-8

[ 中文名 ]:
碘仿

[ 英文名 ]:
iodoform

[中文别名 ]:

[英文别名 ]:

三碘甲烷物理化学性质

[ 密度 ]:
3.9±0.1 g/cm3

[ 沸点 ]:
250.7±8.0 °C at 760 mmHg

[ 熔点 ]:
119 °C

[ 分子式 ]:
CHI3

[ 分子量 ]:
393.732

[ 闪点 ]:
129.0±13.9 °C

[ 精确质量 ]:
393.721191

[ LogP ]:
3.51

[ 外观性状 ]:
黄色粉末或晶体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.851

[ 储存条件 ]:
-20°C

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents, reducing agents. May explode when heated.

[ 水溶解性 ]:
Insoluble.

三碘甲烷MSDS

详细MSDS(安全技术说明书)

三碘甲烷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PB7000000
CHEMICAL NAME :
Methane, triiodo-
CAS REGISTRY NUMBER :
75-47-8
LAST UPDATED :
199801
DATA ITEMS CITED :
34
MOLECULAR FORMULA :
C-H-I3
MOLECULAR WEIGHT :
393.72
WISWESSER LINE NOTATION :
IYII

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
355 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
165 ppm/7H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory stimulation
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1184 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
470 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
630 mg/kg
TOXIC EFFECTS :
Behavioral - antipsychotic Vascular - other changes Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
487 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
606 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
875 mg/kg/35D-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - multiple enzyme effects
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2166 mg/kg/61D-I
TOXIC EFFECTS :
Liver - other changes

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Embryo
REFERENCE :
SHIGAZ Shigaku. Ondotology. (Nippon Shika Daigaku Shigakkai, 1-9-20 Fujimi, Chiyodaku, Tokyo 102, Japan) V.38- 1949- Volume(issue)/page/year: 74,1385,1987 *** REVIEWS *** ACGIH TLV-TWA 10 mg/m3 (0.6 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.6 ppm (10 mg/m3) JAN 1993 OEL-BELGIUM:TWA 0.6 ppm (10 mg/m3) JAN 1993 OEL-DENMARK:TWA 0.2 ppm (3 mg/m3) JAN 1993 OEL-FINLAND:TWA 0.2 ppm (3 mg/m3);STEL 0.6 ppm (10 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 0.6 ppm (10 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 0.2 ppm (3 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.6 ppm (10 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 0.6 ppm (10 mg/m3);STEL 1 ppm (20 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO IODOFORM-air:10H TWA 0.6 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84474 No. of Facilities: 390 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1882 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84474 No. of Facilities: 510 (estimated) No. of Industries: 4 No. of Occupations: 12 No. of Employees: 22584 (estimated) No. of Female Employees: 20381 (estimated)
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三碘甲烷安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302 + H312 + H332-H315-H319-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37-S36/37/39-S22

[ 危险品运输编码 ]:
UN 1851

[ WGK德国 ]:
3

[ RTECS号 ]:
PB7000000

[ 危险类别 ]:
6.1

三碘甲烷合成路线

详细合成路线

三碘甲烷上下游产品

三碘甲烷上游产品

三碘甲烷下游产品

三碘甲烷制备

由丙酮（或乙醇）经卤化、水解而得。先将水、碘化钠及丙酮加入反应锅，加冰降温至10℃。搅拌下缓缓加入次氯酸钠，直至不产生浑浊即达终点，控制温度不超过20℃。静置1h，吸去上层清液，取出碘仿层过滤。滤饼用水洗至中性，再用蒸馏水洗至无氯根为止。然后将其他35-40℃干燥，即得成品。此外，由氯仿与碘甲烷反应也可制备该品。
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三碘甲烷文献

An in vitro evaluation of antimicrobial efficacy of primary root canal filling materials.

J. Clin. Pediatr. Dent. 37(1) , 59-64, (2012)

The present study aimed to evaluate and compare six different materials commonly used for filling the root canals of primary teeth for antimicrobial efficacy against some of the microorganisms commonl...

Application of hollow fiber liquid phase microextraction for simultaneous determination of regulated and emerging iodinated trihalomethanes in drinking water.

J. Chromatogr. A. 1402 , 8-16, (2015)

Trihalomethanes (THMs) are regulated disinfection by-products (DBPs) most commonly analyzed in quality control water supply due to their harmful effects on health. However, few data exist about the co...

Inflammatory effect of green propolis on dental pulp in rats.

Braz. Oral Res. 27(5) , 417-22, (2013)

Pulpotomy in deciduous teeth is a controversial issue, especially with regard to alternative materials used for the direct pulp capping of the root canal pulp tissue. The aim of the present study was ...


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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥88.0/25g ￥258.0/100g

联系人：刘佳

产品详情：三碘甲烷

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥46.0/5g ￥199.0/50g ￥1188.0/500g ￥107.0/25g

联系人：阿拉丁李高志

产品详情：三碘甲烷

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【三碘甲烷】化源网提供三碘甲烷CAS号75-47-8，三碘甲烷MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询三碘甲烷上化源网，专业又轻松。>>电脑版：三碘甲烷

标题：三碘甲烷_MSDS_作用_用途_三碘甲烷CAS号【75-47-8】_化源网 地址：https://m.chemsrc.com/mip/cas/75-47-8_895190.html