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黄柏酮

黄柏酮用途

Obacunone是从沼泽白葡萄柚种子中分离得到的,通过诱导凋亡发挥抗癌作用。

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黄柏酮名称

[ CAS 号 ]:
751-03-1

[ 中文名 ]:
黄柏酮

[ 英文名 ]:
Obacunone

[中文别名 ]:

奥巴叩酮

[英文别名 ]:

OBACUNON
Tricoccin S3
Obacune
CasiMirolide

黄柏酮生物活性

[ 描述 ]:

Obacunone是从沼泽白葡萄柚种子中分离得到的,通过诱导凋亡发挥抗癌作用。

[ 相关类别 ]:

信号通路 >> 细胞凋亡 >> 细胞凋亡

研究领域 >> 癌症

[参考文献]

[1]. Chidambara Murthy KN, et al. Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis. Food Chem Toxicol. 2011 Jul;49(7):1616-25.

黄柏酮物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
626.2±55.0 °C at 760 mmHg

[ 分子式 ]:
C₂₆H₃₀O₇

[ 分子量 ]:
454.512

[ 闪点 ]:
332.5±31.5 °C

[ 精确质量 ]:
454.199158

[ PSA ]:
95.34000

[ LogP ]:
2.91

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.592

[ 储存条件 ]:
2~8℃

黄柏酮安全信息

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
RR1104200

黄柏酮文献

[Simultaneous determination of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex by RP-HPLC].

Zhongguo Zhong Yao Za Zhi 35(16) , 2061-4, (2010)

To develop a HPLC method to determine the content of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex simultaneously. MEHTOD: The separations were carried out at 25 ...

Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis.

Mol. Carcinog. 52(1) , 49-56, (2013)

In this study, we evaluated chemopreventive efficacy of Antitumor B, a Chinese herbal mixture of six plants (Sophora tonkinensis, Polygonum bistorta, Prunella vulgaris, Sonchus arvensis L., Dictamnus ...

Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats.

Biofactors 13(1-4) , 213-8, (2000)

Obacunone and limonin are bitter limonoids in citrus. Their modifying effects on the development of aberrant crypt foci (ACF), the activity of detoxification enzymes, glutathione S-transferase (GST) a...

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黄柏酮

黄柏酮用途

黄柏酮名称

黄柏酮生物活性

黄柏酮物理化学性质

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