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乙酰柠檬酸三乙酯

乙酰柠檬酸三乙酯用途

用作塑料的增塑剂

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乙酰柠檬酸三乙酯名称

[ CAS 号 ]:
77-89-4

[ 中文名 ]:
2-乙酰柠檬酸三乙酯

[ 英文名 ]:
acetyl triethyl citrate

[中文别名 ]:

[英文别名 ]:

Citric Acid Acetyl Triethyl Ester
acetyl triethyl citrate
EINECS 201-066-5
Triethyl 2-acetoxypropane-1,2,3-tricarboxylate
Citroflex A2
Tricarballylic Acid b-Acetoxytributyl Ester
triethyl 2-(acetyloxy)propane-1,2,3-tricarboxylate
Triethyl 2-acetoxy-1,2,3-propanetricarboxylate
MFCD00049378
O-Acetylcitric Acid Triethyl Ester

乙酰柠檬酸三乙酯物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
327.2±37.0 °C at 760 mmHg

[ 熔点 ]:
-42°C

[ 分子式 ]:
C₁₄H₂₂O₈

[ 分子量 ]:
318.320

[ 闪点 ]:
136.9±26.5 °C

[ 精确质量 ]:
318.131470

[ PSA ]:
105.20000

[ LogP ]:
3.73

[ 外观性状 ]:
无色或淡黄色液体

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.453

[ 储存条件 ]:
库房通风低温干燥

乙酰柠檬酸三乙酯MSDS

乙酰柠檬酸三乙酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GE8225000

CHEMICAL NAME :: Citric acid, triethyl ester, acetate

CAS REGISTRY NUMBER :: 77-89-4

BEILSTEIN REFERENCE NO. :: 1804947

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C14-H22-O8

MOLECULAR WEIGHT :: 318.36

WISWESSER LINE NOTATION :: 2OV1XVO2&OV1&1VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IPSTB3 International Polymer Science and Technology. (Rapra Technology Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year: 3,93,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1150 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Vascular - other changes

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,774,1964

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 8510 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,283,1959 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3220 mg/kg/14D-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,774,1964

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 31780 mg/kg/8W-C

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,283,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3176 No. of Facilities: 213 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1251 (estimated)

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乙酰柠檬酸三乙酯安全信息

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S23-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
GE8225000

[ 海关编码 ]:
2918990090

乙酰柠檬酸三乙酯合成路线

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乙酰柠檬酸三乙酯海关

[ 海关编码 ]: 2918990090

[ 中文概述 ]:
2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

乙酰柠檬酸三乙酯文献

Physiological relevant in vitro evaluation of polymer coats for gastroretentive floating tablets.

Eur. J. Pharm. Biopharm. 88(3) , 778-86, (2014)

Gastroretentive drug delivery systems are retained in the stomach for a sufficient time interval, releasing the drug in a controlled manner. According to literature, the floating principle is the most...

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