去乙基利多卡因

单乙基甘氨酰亚胺是利多卡因(HY-B0185)的代谢产物,通过肝脏细胞色素P-450酶对木质素进行氧化N-脱乙基[1]。

[ 描述 ]:

[ 相关类别 ]:

[参考文献]

[ 密度 ]:
1.047g/cm3

[ 沸点 ]:
335.6ºC at 760 mmHg

[ 熔点 ]:
242-245ºC

[ 分子式 ]:
C₁₂H₁₈N₂O

[ 分子量 ]:
206.28

[ 闪点 ]:
127.8ºC

[ 精确质量 ]:
206.14200

[ PSA ]:
41.13000

[ LogP ]:
2.31530

[ 外观性状 ]:
固体

[ 折射率 ]:
1.553

[ 储存条件 ]:
2-8°C

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

AN7740000

CHEMICAL NAME :

2',6'-Acetoxylidide, 2-(ethylamino)-

CAS REGISTRY NUMBER :

7728-40-7

BEILSTEIN REFERENCE NO. :

2417108

LAST UPDATED :

199612

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C12-H18-N2-O

MOLECULAR WEIGHT :

206.32

WISWESSER LINE NOTATION :

2M1MVR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

234 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold

REFERENCE :

JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 179,580,1971

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301

[ 警示性声明 ]:
P301 + P310

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ RTECS号 ]:
AN7740000

[ 海关编码 ]:
2924299090

详细合成路线

去乙基利多卡因上游产品

去乙基利多卡因下游产品

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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更多文献

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：Monoethylglycinexylidineanalyticalstandard

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥1692.0/1mg ￥需询单/1g ￥需询单/1g ￥需询单/1g

联系人：阿拉丁

产品详情：盐酸利多卡因杂质-d5

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