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硫酸锌

硫酸锌用途

用作印染媒染剂、木材防腐剂、造纸漂白剂,还用于医药、人造纤维、电解、电镀、农药及生产锌盐等
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硫酸锌作用

锌是许多酶系统(如碳酸酐酶、乙醇脱氢酶和碱性磷酸酶等)的组成部分,锌缺乏可导致酶功能异常。口服硫酸锌可纠正锌缺乏,恢复酶系统的功能。锌离子能沉淀蛋白质,外用有收敛防腐作用,且能帮助肉芽组织形成。适用于治疗由于锌缺乏引起的肠病性肢端皮炎、口疮、慢性溃疡、结膜炎等。但与青霉胺共用可使后者作用减弱。
血浆、肝脏、腺胰和骨骼组织是锌的快速交换、储存场所,对日常锌水平的变化很敏感。锌影响动物生长、发育和繁殖功能,影响骨骼和血液的形成及核酸、蛋白质和碳水化合物代谢。与毛的生长、皮肤的健康、创伤的愈合有关。在这些组织上,锌主要与酶结合,作为酶必不可少的组成成分和激活剂。锌是碳酸酐酶胰腺的羧基肽酶、谷氨酸和乳酸脱氢酶等的分子组成成分。可激活尿酸酶、肠液中的二肽酶和其他酶。可通过对垂体、促性腺激素的作用间接对繁殖机能发生作用,一水硫酸锌在饲料中可作为锌元素增补剂。
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硫酸锌名称

[ CAS 号 ]:
7733-02-0

[ 中文名 ]:
硫酸锌

[ 英文名 ]:
Zinc sulphate

[英文别名 ]:

硫酸锌物理化学性质

[ 密度 ]:
1.957

[ 沸点 ]:
330ºC at 760 mmHg

[ 熔点 ]:
100ºC

[ 分子式 ]:
O4SZn

[ 分子量 ]:
161.472

[ 精确质量 ]:
159.880875

[ PSA ]:
82.98000

[ LogP ]:
0.42550

[ 外观性状 ]:
无色固体

[ 储存条件 ]:
室温,密封,干燥

[ 水溶解性 ]:
H2O: soluble | Soluble

硫酸锌毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZH5260000
CAS REGISTRY NUMBER :
7733-02-0
LAST UPDATED :
199710
DATA ITEMS CITED :
40
MOLECULAR FORMULA :
O4-S.Zn
MOLECULAR WEIGHT :
161.43
WISWESSER LINE NOTATION :
ZN S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
45 mg/kg/7D-C
TOXIC EFFECTS :
Cardiac - pulse rate increase, without fall in BP Gastrointestinal - other changes Blood - normocytic anemia
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
106 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
180 mg/kg/6W-I
TOXIC EFFECTS :
Blood - other changes
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
3120 mg/kg/43W-I
TOXIC EFFECTS :
Blood - microcytosis with or without anemia Blood - agranulocytosis Nutritional and Gross Metabolic - changes in metals, not otherwise specified
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1710 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
196 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
330 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
69900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
245 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
29060 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
23300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
78 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
66 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
23 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
74 mg/kg/3D-I
TOXIC EFFECTS :
Musculoskeletal - other changes Nutritional and Gross Metabolic - changes in calcium
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1200 mg/kg/60D-C
TOXIC EFFECTS :
Liver - other changes Nutritional and Gross Metabolic - changes in metals, not otherwise specified
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
7110 mg/kg/4W-I
TOXIC EFFECTS :
Gastrointestinal - changes in structure or function of endocrine pancreas Gastrointestinal - hypermotility, diarrhea Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3625 ug/kg/5D-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
333 mg/kg
SEX/DURATION :
female 1-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
34573 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
15 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
2 mg/kg
SEX/DURATION :
female 8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
193 gm/kg
SEX/DURATION :
female 6-20 week(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - abortion Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
200 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,193,1979 *** REVIEWS *** TOXICOLOGY REVIEW FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ. Volume(issue)/page/year: 7,313,1942 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 77220 No. of Facilities: 3067 (estimated) No. of Industries: 52 No. of Occupations: 47 No. of Employees: 40653 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 77220 No. of Facilities: 4755 (estimated) No. of Industries: 52 No. of Occupations: 66 No. of Employees: 89451 (estimated) No. of Female Employees: 27887 (estimated)
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硫酸锌安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319-H412

[ 警示性声明 ]:
P273-P280-P305 + P351 + P338-P337 + P313

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R41;R50/53

[ 安全声明 (欧洲) ]:
S26-S39-S61

[ 危险品运输编码 ]:
UN 3082/9161

[ WGK德国 ]:
3

[ RTECS号 ]:
ZH5260000

[ 海关编码 ]:
2833293000

硫酸锌合成路线

硫酸锌上下游产品

硫酸锌制备

1.将一水硫酸锌ZnSO4·H2O加热至280℃左右使其完全脱水即可生成无水硫酸锌。也可用七水硫酸锌ZnSO4·7H2O为起始物,先在较低的温度下缓慢加热,使其逐步脱水变为一水合物,然后将温度升高至280℃左右。

2.闪锌矿经焙烧后浸提、精炼而得。

3.由硫酸与锌或氧化锌反应而得。

4.主要采用酸解法,以氧化锌或其他含锌化合物为原料,用硫酸分解,再经压滤、浓缩、结晶、分离、烘干而得。

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硫酸锌海关

[ 海关编码 ]: 2833293000

硫酸锌文献

Formulation, in vitro drug release study and anticancer activity of 5-fluorouracil loaded gellan gum microbeads.

Acta Pol. Pharm. 70(1) , 123-7, (2013)

5-Fluorouracil loaded calcium-zinc-gellan and calcium-zinc-gellan-ethyl cellulose microbeads were successfully prepared by simple ionotropic gelation and oil in water ionotropic gelation technique, re...

Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process.

Int. J. Nanomedicine 6 , 2997-3009, (2011)

The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical a...

[Effect of growth factors and some microelements on biosurfactant synthesis of Acinetobacter calcoaceticus IMV B-7241].

Mikrobiol. Z. 75(5) , 18-26, (2013)

The effect of yeast autolysate and microelements on synthesis of surface-active substances (SAS, biosurfactants) was investigated under cultivation of Acinetobacter calcoaceticus IMV B-7241 on various...


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相关化合物

【硫酸锌】化源网提供硫酸锌CAS号7733-02-0,硫酸锌MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询硫酸锌上化源网,专业又轻松。>>电脑版:硫酸锌

标题:硫酸锌_作用_用途_密度_硫酸锌CAS号【7733-02-0】_化源网 地址:https://m.chemsrc.com/mip/cas/7733-02-0_960178.html