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腺苷 3'-单磷酸

腺苷 3'-单磷酸用途

Adenosine 3′-monophosphate (3′-AMP) 是一种核苷酸,是一种环 AMP 产生激动剂。

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腺苷 3'-单磷酸名称

[ CAS 号 ]:
84-21-9

[ 中文名 ]:
腺苷-3’-磷酸

[ 英文名 ]:
3'-Adenylic acid

[中文别名 ]:

[英文别名 ]:

Adenosine-3'-phosphoric Acid
Adenosine 3′-monophosphate
2'and3'-mixture
3'-AMP
synadenylicacid
ADENYLIC ACID,B
Ado-3'-P
A-3'-MP
adenosine-3'-monophosphoric acid
Adenylic Acid b

腺苷 3'-单磷酸生物活性

[ 描述 ]:

Adenosine 3′-monophosphate (3′-AMP) 是一种核苷酸,是一种环 AMP 产生激动剂。

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物

[参考文献]

[1]. S Ohkubo, et al. Effects of AMP derivatives on cyclic AMP levels in NG108-15 cells. Br J Pharmacol. 2000 Mar;129(6):1244-50.

腺苷 3'-单磷酸物理化学性质

[ 密度 ]:
2.3±0.1 g/cm3

[ 沸点 ]:
815.5±75.0 °C at 760 mmHg

[ 熔点 ]:
-210ºC (dec.)

[ 分子式 ]:
C₁₀H₁₄N₅O₇P

[ 分子量 ]:
347.221

[ 闪点 ]:
447.0±37.1 °C

[ 精确质量 ]:
347.063080

[ PSA ]:
195.88000

[ LogP ]:
-1.46

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±3.1 mmHg at 25°C

[ 折射率 ]:
1.905

[ 储存条件 ]:
20°C

腺苷 3'-单磷酸MSDS

腺苷 3'-单磷酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7480320

CHEMICAL NAME :: 3'-Adenylic acid

CAS REGISTRY NUMBER :: 84-21-9

BEILSTEIN REFERENCE NO. :: 0054478

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H14-N5-O7-P

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 60,251,1954

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腺苷 3'-单磷酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22;S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
AU7480320

腺苷 3'-单磷酸合成路线

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腺苷 3'-单磷酸文献

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J. Steroid Biochem. Mol. Biol. 152 , 142-54, (2015)

Androsta-1,4,6-triene-3,17-dione (ATD) is an irreversible steroidal aromatase inhibitor and is marketed as a supplement. It has been reported to effectively reduce estrogen biosynthesis and significan...

Identification of critical ligand binding determinants in Mycobacterium tuberculosis adenosine-5'-phosphosulfate reductase.

J. Med. Chem. 52 , 5485-95, (2009)

Mycobacterium tuberculosis adenosine-5'-phosphosulfate (APS) reductase is an iron-sulfur protein and a validated target to develop new antitubercular agents, particularly for the treatment of latent i...

Pharmacokinetics, tissue distribution, and tentative metabolite identification of sauchinone in mice by microsampling and HPLC-MS/MS methods.

Biol. Pharm. Bull. 38(2) , 218-27, (2015)

Sauchinone, a biologically active lignan found in Saururus chinensis (Saururaceae), exerts various biological activities against jaundice, inflammatory disease, hepatic steatosis, and oxidative injury...

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