7-羟基吩噁嗪酮二戊醚

7-羟基吩噁嗪酮二戊醚用途

Resorufin pentyl ether (Pentoxyresorufin; 7-Pentoxyphenoxazone) 是一种 Resazurin (HY-111391) 类似物。Resorufin pentyl ether 能作为底物来区分不同诱导物对细胞色素 P-450 的诱导。Resorufin pentyl ether 对 N. gonorrhoeae 具有杀菌活性。

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7-羟基吩噁嗪酮二戊醚名称

[ CAS 号 ]:
87687-03-4

[ 中文名 ]:
7-(戊氧基)-3H-吩噁嗪-3-酮

[ 英文名 ]:
Resorufin pentyl ether

[中文别名 ]:

[英文别名 ]:

7-pentoxyphenoxazin-3-one
PENTOXYRESORUFIN
O-Pentylresorufin
7-PENTOXYRESORUFIN
7-PENTYLOXY-3-PHENOXAZONE
7-amoxyphenoxazin-3-one
7-Pentoxyphenoxazone
7-Pentoxy-3H-phenoxazin-3-one
O(7)-PENTYLRESORUFIN

7-羟基吩噁嗪酮二戊醚生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Deanna M. Schmitt, et al. Antibacterial activity of resazurin-based compounds against Neisseria gonorrhoeae in vitro and in vivo. Int J Antimicrob Agents. 2016 Oct; 48(4): 367–372.

[2]. M D Burke, et al. ETHOXY-, PENTOXY- AND BENZYLOXYPHENO~ZONES AND HOMOLOGUES: A SERIES OF SUBSTRATES TO DISTINGUISH BETWEEN DIFFERENT INDUCED CYTOCHROMES P-450. Biochem Pharmacol. 1985 Sep 15;34(18):3337-45.

7-羟基吩噁嗪酮二戊醚物理化学性质

[ 密度 ]:
1.2g/cm3

[ 沸点 ]:
423.6ºC at 760 mmHg

[ 熔点 ]:
151-153ºC

[ 分子式 ]:
C₁₇H₁₇NO₃

[ 分子量 ]:
283.32200

[ 闪点 ]:
183.4ºC

[ 精确质量 ]:
283.12100

[ PSA ]:
52.33000

[ LogP ]:
3.86180

[ 外观性状 ]:
固体

[ 折射率 ]:
1.594

[ 储存条件 ]:
2-8°C

7-羟基吩噁嗪酮二戊醚MSDS

详细MSDS(安全技术说明书)

7-羟基吩噁嗪酮二戊醚安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

7-羟基吩噁嗪酮二戊醚文献

Effect of commercially available green and black tea beverages on drug-metabolizing enzymes and oxidative stress in Wistar rats.

Food Chem. Toxicol. 70 , 120-7, (2014)

The effect of commercially available green tea (GT) and black tea (BT) drinks on drug metabolizing enzymes (DME) and oxidative stress in rats was investigated. Male Wistar rats were fed a laboratory c...

In vivo indirect measurement of cytochrome P450-associated activities in freshwater gastropod molluscs.

Environ. Toxicol. 25(6) , 545-53, (2010)

The cytochrome P450 (CYP) system is widely distributed across phyla and plays a key role in the metabolism of xenobiotic compounds. However, most studies on CYP system were developed on vertebrates an...

Effects of age increase on hepatic expression and activity of cytochrome P450 in male C57BL/6 mice.

Arch. Pharm. Res. 38 , 857-64, (2015)

Effects of aging on hepatic expression and activity of cytochrome P450 (CYP) isoforms were investigated in male mice aged 2, 6, 18, and 30 months. Microsomal protein, total CYP, cytochrome b5 and NADP...

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