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茵芋苷

茵芋苷用途

Skimmin (Umbelliferone glucoside) 是存在于圆锥绣球中的香豆素类物质,可抑制免疫复合物的沉积,具有抗炎活性。

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茵芋苷名称

[ CAS 号 ]:
93-39-0

[ 中文名 ]:
茵芋苷

[ 英文名 ]:
Skimmin

[英文别名 ]:

2H-1-Benzopyran-2-one, 7- (β-D-glucopyranosyloxy)-
7-(Glucosyloxy)coumarin
Skimmin
7-Hydroxycoumarin-7-glucoside
Skimmine
UMBELLIFERONE GLUCOSIDE
2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-
Coumarin, 7-(β-D-glucopyranosyloxy)-
2-Oxo-2H-chromen-7-yl β-D-glucopyranoside
HYDROXYCOUMARIN-GLUCOSIDE,7

茵芋苷生物活性

[ 描述 ]:

Skimmin (Umbelliferone glucoside) 是存在于圆锥绣球中的香豆素类物质,可抑制免疫复合物的沉积,具有抗炎活性。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Zhang S, et al. Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition. Evid Based Complement Alternat Med. 2013;2013:819296.

茵芋苷物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
632.0±55.0 °C at 760 mmHg

[ 熔点 ]:
221-222ºC

[ 分子式 ]:
C₁₅H₁₆O₈

[ 分子量 ]:
324.28

[ 闪点 ]:
239.3±25.0 °C

[ 精确质量 ]:
324.084503

[ PSA ]:
129.59000

[ LogP ]:
-1.50

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±1.9 mmHg at 25°C

[ 折射率 ]:
1.661

[ 储存条件 ]:
室温

茵芋苷安全信息

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

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茵芋苷文献

Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition.

Evid. Based. Complement. Alternat. Med. 2013 , 819296, (2013)

Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent. In the current st...

Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats.

Eur. J. Pharmacol. 692(1-3) , 78-83, (2012)

Skimmin, a major active ingredient from Hydrangea paniculata, was considered to have the possible preventive effect on the progression of diabetic nephropathy based on the traditional Chinese medicine...

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茵芋苷