茵芋苷

• 常用名: 茵芋苷
• 英文名: Skimmin
• CAS号: 93-39-0
• 分子量: 324.28
• 密度: 1.6±0.1 g/cm3
• 沸点: 632.0±55.0 °C at 760 mmHg
• 分子式: C₁₅H₁₆O₈
• 熔点: 221-222ºC
• 闪点: 239.3±25.0 °C

茵芋苷用途

Skimmin (Umbelliferone glucoside) 是存在于圆锥绣球中的香豆素类物质,可抑制免疫复合物的沉积,具有抗炎活性。

茵芋苷名称

• 中文名: 茵芋苷
• 英文名: 7-hydroxycoumarin glucoside

茵芋苷生物活性

• 描述: Skimmin (Umbelliferone glucoside) 是存在于圆锥绣球中的香豆素类物质,可抑制免疫复合物的沉积,具有抗炎活性。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Zhang S, et al. Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition. Evid Based Complement Alternat Med. 2013;2013:819296.

茵芋苷物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 632.0±55.0 °C at 760 mmHg
• 熔点: 221-222ºC
• 分子式: C₁₅H₁₆O₈
• 分子量: 324.28
• 闪点: 239.3±25.0 °C
• 精确质量: 324.084503
• PSA: 129.59000
• LogP: -1.50
• InChIKey: VPAOSFFTKWUGAD-TVKJYDDYSA-N
• SMILES: O=c1ccc2ccc(OC3OC(CO)C(O)C(O)C3O)cc2o1
• 外观性状: 白色 粉末
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.661
• 储存条件: 室温

茵芋苷安全信息

• 危害码 (欧洲): Xi
• 危险品运输编码: NONH for all modes of transport

茵芋苷靶点实验

查看更多实验

实验名称：Antifungal activity against Ceratocystis paradoxa assessed as mycelial growth inhibit... 来源：ChEMBL 靶标：Thielaviopsis paradoxa External Id：CHEMBL3060924

实验名称：Antifungal activity against Alternaria mali assessed as mycelial growth inhibition at... 来源：ChEMBL 靶标：Alternaria mali External Id：CHEMBL3060925

实验名称：Antifungal activity against Athelia rolfsii assessed as mycelial growth inhibition at... 来源：ChEMBL 靶标：Athelia rolfsii External Id：CHEMBL3060926

实验名称：Antifungal activity against Magnaporthe grisea assessed as mycelial growth inhibition... 来源：ChEMBL 靶标：Pyricularia grisea External Id：CHEMBL3060927

实验名称：Antiamnesic activity against Entamoeba histolytica HM1:IMSS after 72 hrs by microdilu... 来源：ChEMBL 靶标：Entamoeba histolytica External Id：CHEMBL941626

实验名称：Small-molecule inhibitors of ST2 (IL1RL1) 来源：20881 靶标：interleukin-1 receptor-like 1 isoform [homo sapiens] External Id：ST2_IL33_Inhibitors_Primary_Screening_77700

实验名称：Antiproliferative activity against human SK-OV-3 cells measured after 21 hrs by MTT a... 来源：ChEMBL 靶标：SK-OV-3 External Id：CHEMBL5513695

实验名称：Cytotoxicity against Spodoptera litura cells assessed as growth inhibition at 20 mg/L... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3060923

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茵芋苷英文别名

• 7-(Glucosyloxy)coumarin
• Skimmin
• 7-Hydroxycoumarin-7-glucoside
• Skimmine
• UMBELLIFERONE GLUCOSIDE
• 2-Oxo-2H-chromen-7-yl β-D-glucopyranoside
• HYDROXYCOUMARIN-GLUCOSIDE,7
• Skimmin (8CI)
• 7-(b-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one