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纳硫酮甲硫醚

纳硫酮甲硫醚名称

[ CAS 号 ]:
93302-47-7

[ 中文名 ]:
纳硫酮甲硫醚

[ 英文名 ]:
NALOXONE METHIODIDE

[英文别名 ]:

N-Methylnaloxonium iodide
Naloxone methiodide

纳硫酮甲硫醚物理化学性质

[ 分子式 ]:
C₂₀H₂₄INO₄

[ 分子量 ]:
469.31300

[ 精确质量 ]:
469.07500

[ PSA ]:
69.59000

[ LogP ]:
2.84120

纳硫酮甲硫醚MSDS

详细MSDS(安全技术说明书)

纳硫酮甲硫醚安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

纳硫酮甲硫醚文献

Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.

J. Neurosci. 35 , 9580-94, (2015)

Due to its distinct pharmacological profile and lower incidence of adverse events compared with other opioids, buprenorphine is considered a safe option for pain and substitution therapy. However, des...

Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice.

PLoS ONE 8 , e74706, (2013)

Opiates are powerful drugs to treat severe pain, and act via mu opioid receptors distributed throughout the nervous system. Their clinical use is hampered by centrally-mediated adverse effects, includ...

Involvement of central opioid systems in human interferon-alpha induced immobility in the mouse forced swimming test.

Br. J. Pharmacol. 130 , 1269-1274, (2000)

1. We investigated the mechanism by which human interferon-alpha (IFN-alpha) increases the immobility time in a forced swimming test, an animal model of depression. 2. Central administration of IFN-al...

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