驱蚊醇
驱蚊醇用途
用于有机合成，可制取聚酯树脂、聚酯增塑剂、聚氨酯树脂等。该品对蚊蝇是有效的驱虫剂，也可用于生产化妆品或作为油墨溶剂。
驱蚊醇名称
[ CAS 号 ]:
94-96-2
[ 中文名 ]:
驱蚊醇
[ 英文名 ]:
Etohexadiol
[中文别名 ]:
- 2-乙基-1,3-己二醇
- 2-乙-1,3-己二醇
- 2-乙基己烷-1,3-二醇
- 2-乙基-1,3-已二醇
- 2-乙-3-丙-1,3-丙二醇
- 2-乙基-3-丙基-1,3-丙二醇
- 2-乙基-1,3-己二醇(混合异构)
[英文别名 ]:
- 1,3-Hexanediol, 2-ethyl-
- 2-Ethyl-1,3-hexanediol
- QY3&Y2&1Q
- (2Ξ,3Ξ)-2-ethylhexane-1,3-diol
- 2-Ethylhexan-1,3-diol
- (2RS,3RS
- EINECS 202-377-9
- ethohexadiol
- Etohexadiol
- MFCD00004578
驱蚊醇物理化学性质
[ 密度 ]:
0.9±0.1 g/cm3
[ 沸点 ]:
243.0±8.0 °C at 760 mmHg
[ 熔点 ]:
-40 °C
[ 分子式 ]:
C8H18O2
[ 分子量 ]:
146.227
[ 闪点 ]:
129.4±0.0 °C
[ 精确质量 ]:
146.130676
[ PSA ]:
40.46000
[ LogP ]:
1.25
[ 外观性状 ]:
无色,略粘性液体
[ 蒸汽密度 ]:
5 (vs air)
[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C
[ 折射率 ]:
1.451
[ 储存条件 ]:
包装完整、轻装轻放,库房通风、远离明火、高温、与氧化剂分开存放
[ 水溶解性 ]:
42 g/L (20 ºC)
驱蚊醇MSDS
驱蚊醇毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MO2625000
- CHEMICAL NAME :
- 1,3-Hexanediol, 2-ethyl-
- CAS REGISTRY NUMBER :
- 94-96-2
- BEILSTEIN REFERENCE NO. :
- 1735324
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 19
- MOLECULAR FORMULA :
- C8-H18-O2
- MOLECULAR WEIGHT :
- 146.26
- WISWESSER LINE NOTATION :
- QY3&Y2&1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,731,1969
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,52,1978
- TYPE OF TEST :
- LC - Lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4800 ppm/8H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/3/1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,52,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year: -,508,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 1,208,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1900 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >10 mL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 1400 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 180 mL/kg/13W-I
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure) Related to Chronic Data - death
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 20 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1288-0778
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 20 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1288-0778
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- DOSE :
- 40 mL/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- JTOTDO Journal of Toxicology, Cutaneous and Ocular Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1982- Volume(issue)/page/year: 13,203,1994 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2395 No. of Facilities: 656 (estimated) No. of Industries: 10 No. of Occupations: 23 No. of Employees: 8430 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2395 No. of Facilities: 769 (estimated) No. of Industries: 17 No. of Occupations: 17 No. of Employees: 18193 (estimated) No. of Female Employees: 2769 (estimated)
驱蚊醇安全信息
[ 符号 ]:
GHS05, GHS07
[ 信号词 ]:
Danger
[ 危害声明 ]:
H302 + H312-H318
[ 警示性声明 ]:
P280-P301 + P312 + P330-P305 + P351 + P338 + P310
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xi:Irritant;
[ 风险声明 (欧洲) ]:
R41
[ 安全声明 (欧洲) ]:
S25-S26-S39-S46
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
1
[ RTECS号 ]:
MO2625000
[ 海关编码 ]:
29053980
驱蚊醇合成路线
驱蚊醇上下游产品
驱蚊醇上游产品
驱蚊醇下游产品
驱蚊醇制备
1.先由丙烯合成丁醛，在碱或酸的催化下，丁醛自身缩合生成2-乙基-3-羟基已醛。这一化合物很不稳定，经加氢即得2-乙基-1,3-已二醇。
2.制法：
2-乙基-3-羟基己醛(3)：于装有搅拌器、温度计、滴液漏斗的反应瓶中，加入正己醛(3)260g(3.6mol0)，乙醚150mL，冰盐浴冷却至-3℃，开始滴加30mL(10%)的醛氧化钾溶液，开始时滴加要缓慢，以防温度超过8℃。约3h加完。加完后再搅拌反应5h。分出有机层，水洗三次，无水硫酸钠干燥。回收乙醚，减压蒸出低沸物，得粗产品2-乙基-3-羟基己醛(3)200～220g。2-乙基-1,3-己二醇(1)：于装有搅拌器、回流冷凝器的反应瓶中，加入铝屑33g(1.2mol),无水异丙醇300mL，加入碘0.1g，水浴加热，生成异丙醇铝，并有大量氢气放出，当大部分的铝参加反应后，再加入无水异丙醇300mL。回流6h以使反应完全。反应体系呈深灰色。冷后加入前面制得的2-乙基-3-羟基己醛(3),安上有填充物的分馏柱，不断蒸出生成的丙酮。随着反应的的进行，丙酮逐渐蒸完，异丙醇蒸出，直至柱顶温度达到80℃(此时为异丙醇，可回收再利用)。冷却，以15%的烯硫酸调至弱酸性，有油状物析出。分出油状物，水洗三次，无水硫酸钠干燥，而后进行分馏，收集238～242℃的馏分，得2-乙基-1,3-己二醇(1)60g,收率23%。
驱蚊醇海关
[ 海关编码 ]: 2905399010
[ 中文概述 ]:
2905399010 驱蚊醇。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:5.5%。普通关税:30.0%
[ Summary ]:
2905399010 2-ethylhexane-1,3-diol。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%
驱蚊醇文献
J. Med. Entomol. 28(3) , 417-20, (1991)
Five repellents were evaluated against Anopheles albimanus Wiedemann An. freeborni Aitken, An. gambiae Giles, and An. stephensi Liston, using a "free choice," dose-response testing procedure on rabbit...
The acute toxicity and primary irritancy of 2-ethyl-1,3-hexanediol.Vet. Hum. Toxicol. 27(6) , 491-5, (1985)
2-Ethyl-1,3-hexanediol (EHD), an insect repellant, was found to have acute peroral LD50 values in the rat of 9.85 ml/kg (males) and 4.92 ml/kg (females). Acute percutaneous LD50 values in the rabbit w...
Prevention of Lyme disease.Am. J. Hosp. Pharm. 49(5) , 1164-73, (1992)
Lyme disease and the use of tick repellents and physical protective measures to prevent the disease are discussed. Lyme disease is a multiple-organ-system, immune-mediated inflammatory disorder transm...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：2-乙基-1,3-己二醇
公司名：南通润丰石油化工有限公司
区域：南通市崇川区
价格：
￥需询单/1kg
￥需询单/1ton
联系人：曹经理
产品详情：2-乙基-1,3-己二醇
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥578.0/500ml
￥188.0/100ml
联系人：刘佳
产品详情：2-乙基-1,3-己二醇
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥54.0/25ml
￥100.0/100ml
￥261.0/500ml
￥760.0/2500ml
联系人：夏言
产品详情：[Perfemiker]2-乙基-1，3-己二醇,98%
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥95.9/100ml
￥1226.9/3l
￥50.9/25ml
￥261.9/500ml
联系人：阿拉丁
产品详情：2-乙基-1,3-己二醇
查看所有供应商请点击：
相关化合物
【驱蚊醇】化源网提供驱蚊醇CAS号94-96-2，驱蚊醇MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询驱蚊醇上化源网，专业又轻松。>>电脑版：驱蚊醇
标题：驱蚊醇_MSDS_用途_密度_驱蚊醇CAS号【94-96-2】_化源网 地址：https://m.chemsrc.com/mip/cas/94-96-2_820854.html