3-吲哚甲酸甲酯

3-吲哚甲酸甲酯用途

Methyl indole-3-carboxylate 是一种从 Sorangium cellulosum Soce895 菌株中分离出来的天然产物。Methyl indole-3-carboxylate 对革兰氏阳性诺卡氏菌 (Nocardia sp) 表现出较弱的活性,MIC 值为 33.3 μg/mL。

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3-吲哚甲酸甲酯名称

[ CAS 号 ]:
942-24-5

[ 中文名 ]:
吲哚-3-甲酸甲酯

[ 英文名 ]:
Methyl 3-indolecarboxylate

[中文别名 ]:

[英文别名 ]:

Methyl 1H-indole-3-carboxylate
Indole-3-carboxylic acid, methyl ester
1H-Indole-3-carboxylic acid, methyl ester
METHYL INDOLE-3-CARBOXYLATE
MFCD00189407

3-吲哚甲酸甲酯生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Rolf Jansen, et al. Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. J Nat Prod. 2014 Nov 26;77(11):2545-52.

3-吲哚甲酸甲酯物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
331.7±15.0 °C at 760 mmHg

[ 熔点 ]:
149-152 °C(lit.)

[ 分子式 ]:
C₁₀H₉NO₂

[ 分子量 ]:
175.184

[ 闪点 ]:
154.4±20.4 °C

[ 精确质量 ]:
175.063324

[ PSA ]:
42.09000

[ LogP ]:
2.54

[ 外观性状 ]:
淡粉红色粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.639

[ 储存条件 ]:
室温

3-吲哚甲酸甲酯MSDS

3-吲哚甲酸甲酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933990090

3-吲哚甲酸甲酯合成路线

3-吲哚甲酸甲酯上下游产品

3-吲哚甲酸甲酯上游产品

3-吲哚甲酸甲酯下游产品

3-吲哚甲酸甲酯海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3-吲哚甲酸甲酯文献

Regioselective dibromination of methyl indole-3-carboxylate and application in the synthesis of 5,6-dibromoindoles.

Org. Biomol. Chem. 9(14) , 5021-3, (2011)

Treatment of methyl indole-3-carboxylate with bromine in acetic acid gives methyl 5,6-dibromoindole-3-carboxylate regioselectively, from which the parent 5,6-dibromoindole can be accessed via a one-po...

Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria.

J. Nat. Prod. 77(11) , 2545-52, (2014)

Nannozinones A (1) and B (2) were discovered as metabolites of the recently isolated Nannocystis pusilla strain MNa10913 belonging to the poorly studied myxobacterial family Nannocystaceae. In contras...

Methyl indole-3-carboxylate. Hu SC, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 61(6) , o1654-o1656, (2005)

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