3,4-二甲酚
3,4-二甲酚用途
3,4-二甲酚名称
[ CAS 号 ]:
95-65-8
[ 中文名 ]:
3,4-二甲基苯酚
[ 英文名 ]:
3,4-Xylenol
[中文别名 ]:
[英文别名 ]:
- 1-HYDROXY-3,4-DIMETHYLBENZENE
- 4-Hydroxy-1,2-dimethylbenzene
- 1,2-Dimethyl-4-hydroxybenzene
- as-o-xylenol
- 3,4-Dimethyl-phenol
- 4-Hydroxy-o-xylene
- 3,4-DMP
- 3,4-Dimethylphenol
- EINECS 202-439-5
- 3,4-Xylenol
3,4-二甲酚物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
226.9±0.0 °C at 760 mmHg
[ 熔点 ]:
65-68 °C
[ 分子式 ]:
C8H10O
[ 分子量 ]:
122.164
[ 闪点 ]:
94.0±7.2 °C
[ 精确质量 ]:
122.073166
[ PSA ]:
20.23000
[ LogP ]:
2.40
[ 外观性状 ]:
白色晶体
[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C
[ 折射率 ]:
1.540
[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开存放
[ 水溶解性 ]:
SLIGHTLY SOLUBLE
3,4-二甲酚MSDS
3,4-二甲酚毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ZE6300000
- CHEMICAL NAME :
- 3,4-Xylenol
- CAS REGISTRY NUMBER :
- 95-65-8
- BEILSTEIN REFERENCE NO. :
- 1099267
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C8-H10-O
- MOLECULAR WEIGHT :
- 122.18
- WISWESSER LINE NOTATION :
- QR C1 D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 727 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPPAF Gigiena Truda i Professional'naya Patologiya v Estonskoi SSR. Labor Hygiene and Occupational Pathology in the Estonian SSR. (Institut Eksperimental'noi i Klinicheskoi Meditsiny Ministerstva Zdravookhraneniya Estonskoi SSR, Tallinn, USSR) V.8- 1972- Volume(issue)/page/year: 8,145,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Kidney, Ureter, Bladder - other changes in urine composition Skin and Appendages - hair
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533431
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(7-9),329,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Skin and Appendages - hair
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533431
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(7-9),329,1968 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5075 mg/kg/10W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Endocrine - changes in spleen weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(7-9),329,1968 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4000 mg/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 19,413,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1582 No. of Facilities: 61 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 136 (estimated) No. of Female Employees: 56 (estimated)
3,4-二甲酚安全信息
[ 符号 ]:
GHS05, GHS06, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H301-H311-H314-H411
[ 警示性声明 ]:
P273-P280-P301 + P310-P305 + P351 + P338-P310
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
T:Toxic
[ 风险声明 (欧洲) ]:
R24/25;R34;R51/53
[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S61
[ 危险品运输编码 ]:
UN 2261 6.1/PG 2
[ WGK德国 ]:
3
[ RTECS号 ]:
ZE6300000
[ 包装等级 ]:
II
[ 危险类别 ]:
6.1
[ 海关编码 ]:
2907299090
3,4-二甲酚合成路线
3,4-二甲酚上下游产品
3,4-二甲酚上游产品
3,4-二甲酚下游产品
3,4-二甲酚制备
1. 由煤焦油的洗油馏分，经氢氧化钠皂化、硫酸酸化得到的粗酚中含有苯酚、甲酚和二甲酚。由粗酚分离可得混合二甲酚，通过精馏切除3,5-二甲酚，将剩余物精馏，收集225-229℃馏分、冷却结晶，离心分离即得3,4-二甲酚。另外以邻二甲苯为原料，经磺化、碱熔、酸析、蒸馏，也可得到该品。
2. 烟草：OR，26。
3,4-二甲酚海关
[ 海关编码 ]: 2907199090
[ 中文概述 ]:
2907199090 其他一元酚. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
3,4-二甲酚文献
J. Agric. Food Chem. 63 , 5670-81, (2015)
In sparkling wines, mannoproteins released during yeast autolysis largely affect their final quality. This process is very slow and may take several months. The aim of this work was to study the effec...
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).J. Med. Chem. 48 , 3269-79, (2005)
Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm...
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.Bioorg. Med. Chem. 15 , 6943-55, (2007)
A set of 116 structurally very diverse compounds, mainly drugs, was characterized by 1630 molecular descriptors. The biological property modelled in this study was the transdermal permeability coeffic...
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公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥178.0/100g
联系人：刘佳
产品详情：3,4-二甲苯酚
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
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联系人：阿拉丁李高志
产品详情：3,4-二甲酚标准溶液
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相关化合物
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