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1-硫代甘油

1-硫代甘油用途

1-硫代甘油是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

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1-硫代甘油名称

[ CAS 号 ]:
96-27-5

[ 中文名 ]:
1-硫代甘油

[ 英文名 ]:
3-Mercaptopropane-1,2-diol

[中文别名 ]:

[英文别名 ]:

a-Thioglycerin
Glycerol, 1-thio-
EINECS 202-495-0
1-Mercapto-2,3-propanediol
1-Monothioglycerol
Thioglycerol
MFCD00004879
3-Sulfanyl-1,2-propanediol
1,2-Dihydroxy-3-mercaptopropane
1,2-Propanediol, 3-mercapto-

1-硫代甘油生物活性

[ 描述 ]:

1-硫代甘油是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

1-硫代甘油物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
247.0±0.0 °C at 760 mmHg

[ 分子式 ]:
C₃H₈O₂S

[ 分子量 ]:
108.159

[ 闪点 ]:
126.3±24.6 °C

[ 精确质量 ]:
108.024498

[ PSA ]:
79.26000

[ LogP ]:
-0.92

[ 外观性状 ]:
透明至淡黄色粘性溶液

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.526

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
slightly soluble

1-硫代甘油MSDS

1-硫代甘油毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TY8140000

CHEMICAL NAME :: 1,2-Propanediol, 3-mercapto-

CAS REGISTRY NUMBER :: 96-27-5

BEILSTEIN REFERENCE NO. :: 1732046

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C3-H8-O2-S

MOLECULAR WEIGHT :: 108.17

WISWESSER LINE NOTATION :: SH1YQ1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 390 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 340 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 220 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 gm/kg/4W-I

TOXIC EFFECTS :: Endocrine - changes in thyroid weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 1925 mg/kg

SEX/DURATION :: male 35 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 2000 ppm

REFERENCE :: AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 19,556,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83967 No. of Facilities: 213 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 1912 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83967 No. of Facilities: 1464 (estimated) No. of Industries: 20 No. of Occupations: 24 No. of Employees: 16561 (estimated) No. of Female Employees: 6744 (estimated)

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1-硫代甘油安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H311-H315-H319-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P312

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S23

[ 危险品运输编码 ]:
UN 2810 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
TY8140000

[ 危险类别 ]:
6.1

[ 海关编码 ]:
29309070

1-硫代甘油合成路线

1-硫代甘油上下游产品

1-硫代甘油上游产品

1-硫代甘油下游产品

1-硫代甘油海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

1-硫代甘油文献

UNC45A localizes to centrosomes and regulates cancer cell proliferation through ChK1 activation.

Cancer Lett. 357(1) , 114-20, (2014)

The UCS family of proteins regulates cellular functions through their interactions with myosin. Here we show that one member of this family, UNC45A, is also a novel centrosomal protein. UNC45A is requ...

Compact and blinking-suppressed quantum dots for single-particle tracking in live cells.

J. Phys. Chem. B 118(49) , 14140-7, (2014)

Quantum dots (QDs) offer distinct advantages over organic dyes and fluorescent proteins for biological imaging applications because of their brightness, photostability, and tunability. However, a majo...

Optical reconstruction of murine colorectal mucosa at cellular resolution.

Am. J. Physiol. Gastrointest. Liver Physiol. 308 , G721-35, (2015)

The mucosal layer of the colon is a unique and dynamic site where host cells interface with one another and the microbiome, with major implications for physiology and disease. However, the cellular me...

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