1-硫代甘油
1-硫代甘油用途
1-硫代甘油名称
[ CAS 号 ]:
96-27-5
[ 中文名 ]:
1-硫代甘油
[ 英文名 ]:
3-Mercaptopropane-1,2-diol
[中文别名 ]:
[英文别名 ]:
- a-Thioglycerin
- Glycerol, 1-thio-
- EINECS 202-495-0
- 1-Mercapto-2,3-propanediol
- 1-Monothioglycerol
- Thioglycerol
- MFCD00004879
- 3-Sulfanyl-1,2-propanediol
- 1,2-Dihydroxy-3-mercaptopropane
- 1,2-Propanediol, 3-mercapto-
1-硫代甘油生物活性
1-硫代甘油物理化学性质
[ 密度 ]:
1.2±0.1 g/cm3
[ 沸点 ]:
247.0±0.0 °C at 760 mmHg
[ 分子式 ]:
C3H8O2S
[ 分子量 ]:
108.159
[ 闪点 ]:
126.3±24.6 °C
[ 精确质量 ]:
108.024498
[ PSA ]:
79.26000
[ LogP ]:
-0.92
[ 外观性状 ]:
透明至淡黄色粘性溶液
[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C
[ 折射率 ]:
1.526
[ 储存条件 ]:
2-8°C
[ 水溶解性 ]:
slightly soluble
1-硫代甘油MSDS
1-硫代甘油毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TY8140000
- CHEMICAL NAME :
- 1,2-Propanediol, 3-mercapto-
- CAS REGISTRY NUMBER :
- 96-27-5
- BEILSTEIN REFERENCE NO. :
- 1732046
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C3-H8-O2-S
- MOLECULAR WEIGHT :
- 108.17
- WISWESSER LINE NOTATION :
- SH1YQ1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 390 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 340 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 220 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 gm/kg/4W-I
- TOXIC EFFECTS :
- Endocrine - changes in thyroid weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1925 mg/kg
- SEX/DURATION :
- male 35 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 2000 ppm
- REFERENCE :
- AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 19,556,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83967 No. of Facilities: 213 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 1912 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83967 No. of Facilities: 1464 (estimated) No. of Industries: 20 No. of Occupations: 24 No. of Employees: 16561 (estimated) No. of Female Employees: 6744 (estimated)
1-硫代甘油安全信息
[ 符号 ]:
GHS06
[ 信号词 ]:
Danger
[ 危害声明 ]:
H302-H311-H315-H319-H335
[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P312
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xi:Irritant;
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S26-S36-S23
[ 危险品运输编码 ]:
UN 2810 6.1/PG 3
[ WGK德国 ]:
3
[ RTECS号 ]:
TY8140000
[ 危险类别 ]:
6.1
[ 海关编码 ]:
29309070
1-硫代甘油合成路线
1-硫代甘油上下游产品
1-硫代甘油上游产品
1-硫代甘油下游产品
1-硫代甘油海关
[ 海关编码 ]: 2930909090
[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
1-硫代甘油文献
Cancer Lett. 357(1) , 114-20, (2014)
The UCS family of proteins regulates cellular functions through their interactions with myosin. Here we show that one member of this family, UNC45A, is also a novel centrosomal protein. UNC45A is requ...
Compact and blinking-suppressed quantum dots for single-particle tracking in live cells.J. Phys. Chem. B 118(49) , 14140-7, (2014)
Quantum dots (QDs) offer distinct advantages over organic dyes and fluorescent proteins for biological imaging applications because of their brightness, photostability, and tunability. However, a majo...
Optical reconstruction of murine colorectal mucosa at cellular resolution.Am. J. Physiol. Gastrointest. Liver Physiol. 308 , G721-35, (2015)
The mucosal layer of the colon is a unique and dynamic site where host cells interface with one another and the microbiome, with major implications for physiology and disease. However, the cellular me...
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产品详情:1-Thioglycerol
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产品详情:1-硫代甘油
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¥1525.0/22kg
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产品详情:3-巯基-1,2-丙二醇
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相关化合物
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